@inproceedings{zhang-etal-2024-knowledge-aware-attention,
title = "Knowledge-aware Attention Network for Medication Effectiveness Prediction",
author = "Zhang, Yingying and
Wu, Xian and
Zhang, Yu and
Zheng, Yefeng",
editor = "Calzolari, Nicoletta and
Kan, Min-Yen and
Hoste, Veronique and
Lenci, Alessandro and
Sakti, Sakriani and
Xue, Nianwen",
booktitle = "Proceedings of the 2024 Joint International Conference on Computational Linguistics, Language Resources and Evaluation (LREC-COLING 2024)",
month = may,
year = "2024",
address = "Torino, Italia",
publisher = "ELRA and ICCL",
url = "https://aclanthology.org/2024.lrec-main.856",
pages = "9799--9809",
abstract = "The first 24 hours{'} medication plan is critical to patients with serious or life-threatening illnesses and injuries. An appropriate medication can result in a lower mortality, a shorter length stay and a higher APACHE score. However, in clinical practice, the medication plan is often error-prone, especially when a decision must be made quickly for life-threatening situations in Intensive Care Unit (ICU). Therefore, predicting the effectiveness of the first 24 hours{'} medication plan is of great importance in assisting doctors to make proper decisions. Existing effectiveness prediction works usually focus on one specific medicine, one specific disease, or one specific lab test, making it hard to extend to general medicines and diseases in hospital/ICU scenarios. In this paper, we propose to predict medication effectiveness of the first 24 hours in hospital/ICU based on patients{'} information. Specifically, we use a knowledge enhanced module to incorporate external knowledge about medications and a medical feature learning module to determine the interaction between diagnosis and medications. To handle the data imbalance problem, we further optimize the proposed model with a contrastive loss. Extensive experimental results on a public dataset show that our model can significantly outperform state-of-the-art methods.",
}
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<abstract>The first 24 hours’ medication plan is critical to patients with serious or life-threatening illnesses and injuries. An appropriate medication can result in a lower mortality, a shorter length stay and a higher APACHE score. However, in clinical practice, the medication plan is often error-prone, especially when a decision must be made quickly for life-threatening situations in Intensive Care Unit (ICU). Therefore, predicting the effectiveness of the first 24 hours’ medication plan is of great importance in assisting doctors to make proper decisions. Existing effectiveness prediction works usually focus on one specific medicine, one specific disease, or one specific lab test, making it hard to extend to general medicines and diseases in hospital/ICU scenarios. In this paper, we propose to predict medication effectiveness of the first 24 hours in hospital/ICU based on patients’ information. Specifically, we use a knowledge enhanced module to incorporate external knowledge about medications and a medical feature learning module to determine the interaction between diagnosis and medications. To handle the data imbalance problem, we further optimize the proposed model with a contrastive loss. Extensive experimental results on a public dataset show that our model can significantly outperform state-of-the-art methods.</abstract>
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%0 Conference Proceedings
%T Knowledge-aware Attention Network for Medication Effectiveness Prediction
%A Zhang, Yingying
%A Wu, Xian
%A Zhang, Yu
%A Zheng, Yefeng
%Y Calzolari, Nicoletta
%Y Kan, Min-Yen
%Y Hoste, Veronique
%Y Lenci, Alessandro
%Y Sakti, Sakriani
%Y Xue, Nianwen
%S Proceedings of the 2024 Joint International Conference on Computational Linguistics, Language Resources and Evaluation (LREC-COLING 2024)
%D 2024
%8 May
%I ELRA and ICCL
%C Torino, Italia
%F zhang-etal-2024-knowledge-aware-attention
%X The first 24 hours’ medication plan is critical to patients with serious or life-threatening illnesses and injuries. An appropriate medication can result in a lower mortality, a shorter length stay and a higher APACHE score. However, in clinical practice, the medication plan is often error-prone, especially when a decision must be made quickly for life-threatening situations in Intensive Care Unit (ICU). Therefore, predicting the effectiveness of the first 24 hours’ medication plan is of great importance in assisting doctors to make proper decisions. Existing effectiveness prediction works usually focus on one specific medicine, one specific disease, or one specific lab test, making it hard to extend to general medicines and diseases in hospital/ICU scenarios. In this paper, we propose to predict medication effectiveness of the first 24 hours in hospital/ICU based on patients’ information. Specifically, we use a knowledge enhanced module to incorporate external knowledge about medications and a medical feature learning module to determine the interaction between diagnosis and medications. To handle the data imbalance problem, we further optimize the proposed model with a contrastive loss. Extensive experimental results on a public dataset show that our model can significantly outperform state-of-the-art methods.
%U https://aclanthology.org/2024.lrec-main.856
%P 9799-9809
Markdown (Informal)
[Knowledge-aware Attention Network for Medication Effectiveness Prediction](https://aclanthology.org/2024.lrec-main.856) (Zhang et al., LREC-COLING 2024)
ACL