SUPP.AI: finding evidence for supplement-drug interactions

Lucy Wang, Oyvind Tafjord, Arman Cohan, Sarthak Jain, Sam Skjonsberg, Carissa Schoenick, Nick Botner, Waleed Ammar


Abstract
Dietary supplements are used by a large portion of the population, but information on their pharmacologic interactions is incomplete. To address this challenge, we present SUPP.AI, an application for browsing evidence of supplement-drug interactions (SDIs) extracted from the biomedical literature. We train a model to automatically extract supplement information and identify such interactions from the scientific literature. To address the lack of labeled data for SDI identification, we use labels of the closely related task of identifying drug-drug interactions (DDIs) for supervision. We fine-tune the contextualized word representations of the RoBERTa language model using labeled DDI data, and apply the fine-tuned model to identify supplement interactions. We extract 195k evidence sentences from 22M articles (P=0.82, R=0.58, F1=0.68) for 60k interactions. We create the SUPP.AI application for users to search evidence sentences extracted by our model. SUPP.AI is an attempt to close the information gap on dietary supplements by making up-to-date evidence on SDIs more discoverable for researchers, clinicians, and consumers. An informational video on how to use SUPP.AI is available at: https://youtu.be/dR0ucKdORwc
Anthology ID:
2020.acl-demos.41
Volume:
Proceedings of the 58th Annual Meeting of the Association for Computational Linguistics: System Demonstrations
Month:
July
Year:
2020
Address:
Online
Venue:
ACL
SIG:
Publisher:
Association for Computational Linguistics
Note:
Pages:
362–371
Language:
URL:
https://aclanthology.org/2020.acl-demos.41
DOI:
10.18653/v1/2020.acl-demos.41
Bibkey:
Cite (ACL):
Lucy Wang, Oyvind Tafjord, Arman Cohan, Sarthak Jain, Sam Skjonsberg, Carissa Schoenick, Nick Botner, and Waleed Ammar. 2020. SUPP.AI: finding evidence for supplement-drug interactions. In Proceedings of the 58th Annual Meeting of the Association for Computational Linguistics: System Demonstrations, pages 362–371, Online. Association for Computational Linguistics.
Cite (Informal):
SUPP.AI: finding evidence for supplement-drug interactions (Wang et al., ACL 2020)
Copy Citation:
PDF:
https://aclanthology.org/2020.acl-demos.41.pdf
Video:
 http://slideslive.com/38928607
Code
 allenai/sdi-detection
Data
DDI