Trialstreamer: Mapping and Browsing Medical Evidence in Real-Time

Benjamin Nye, Ani Nenkova, Iain Marshall, Byron C. Wallace


Abstract
We introduce Trialstreamer, a living database of clinical trial reports. Here we mainly describe the evidence extraction component; this extracts from biomedical abstracts key pieces of information that clinicians need when appraising the literature, and also the relations between these. Specifically, the system extracts descriptions of trial participants, the treatments compared in each arm (the interventions), and which outcomes were measured. The system then attempts to infer which interventions were reported to work best by determining their relationship with identified trial outcome measures. In addition to summarizing individual trials, these extracted data elements allow automatic synthesis of results across many trials on the same topic. We apply the system at scale to all reports of randomized controlled trials indexed in MEDLINE, powering the automatic generation of evidence maps, which provide a global view of the efficacy of different interventions combining data from all relevant clinical trials on a topic. We make all code and models freely available alongside a demonstration of the web interface.
Anthology ID:
2020.acl-demos.9
Volume:
Proceedings of the 58th Annual Meeting of the Association for Computational Linguistics: System Demonstrations
Month:
July
Year:
2020
Address:
Online
Editors:
Asli Celikyilmaz, Tsung-Hsien Wen
Venue:
ACL
SIG:
Publisher:
Association for Computational Linguistics
Note:
Pages:
63–69
Language:
URL:
https://aclanthology.org/2020.acl-demos.9
DOI:
10.18653/v1/2020.acl-demos.9
Bibkey:
Cite (ACL):
Benjamin Nye, Ani Nenkova, Iain Marshall, and Byron C. Wallace. 2020. Trialstreamer: Mapping and Browsing Medical Evidence in Real-Time. In Proceedings of the 58th Annual Meeting of the Association for Computational Linguistics: System Demonstrations, pages 63–69, Online. Association for Computational Linguistics.
Cite (Informal):
Trialstreamer: Mapping and Browsing Medical Evidence in Real-Time (Nye et al., ACL 2020)
Copy Citation:
PDF:
https://aclanthology.org/2020.acl-demos.9.pdf
Video:
 http://slideslive.com/38928619
Code
 bepnye/evidence_extraction
Data
EBM-NLPEvidence Inference