Exploring the Boundaries of GPT-4 in Radiology

Qianchu Liu, Stephanie Hyland, Shruthi Bannur, Kenza Bouzid, Daniel Castro, Maria Wetscherek, Robert Tinn, Harshita Sharma, Fernando Pérez-García, Anton Schwaighofer, Pranav Rajpurkar, Sameer Khanna, Hoifung Poon, Naoto Usuyama, Anja Thieme, Aditya Nori, Matthew Lungren, Ozan Oktay, Javier Alvarez-Valle


Abstract
The recent success of general-domain large language models (LLMs) has significantly changed the natural language processing paradigm towards a unified foundation model across domains and applications. In this paper, we focus on assessing the performance of GPT-4, the most capable LLM so far, on the text-based applications for radiology reports, comparing against state-of-the-art (SOTA) radiology-specific models. Exploring various prompting strategies, we evaluated GPT-4 on a diverse range of common radiology tasks and we found GPT-4 either outperforms or is on par with current SOTA radiology models. With zero-shot prompting, GPT-4 already obtains substantial gains ( 10% absolute improvement) over radiology models in temporal sentence similarity classification (accuracy) and natural language inference (F1). For tasks that require learning dataset-specific style or schema (e.g. findings summarisation), GPT-4 improves with example-based prompting and matches supervised SOTA. Our extensive error analysis with a board-certified radiologist shows GPT-4 has a sufficient level of radiology knowledge with only occasional errors in complex context that require nuanced domain knowledge. For findings summarisation, GPT-4 outputs are found to be overall comparable with existing manually-written impressions.
Anthology ID:
2023.emnlp-main.891
Volume:
Proceedings of the 2023 Conference on Empirical Methods in Natural Language Processing
Month:
December
Year:
2023
Address:
Singapore
Editors:
Houda Bouamor, Juan Pino, Kalika Bali
Venue:
EMNLP
SIG:
Publisher:
Association for Computational Linguistics
Note:
Pages:
14414–14445
Language:
URL:
https://aclanthology.org/2023.emnlp-main.891
DOI:
10.18653/v1/2023.emnlp-main.891
Bibkey:
Cite (ACL):
Qianchu Liu, Stephanie Hyland, Shruthi Bannur, Kenza Bouzid, Daniel Castro, Maria Wetscherek, Robert Tinn, Harshita Sharma, Fernando Pérez-García, Anton Schwaighofer, Pranav Rajpurkar, Sameer Khanna, Hoifung Poon, Naoto Usuyama, Anja Thieme, Aditya Nori, Matthew Lungren, Ozan Oktay, and Javier Alvarez-Valle. 2023. Exploring the Boundaries of GPT-4 in Radiology. In Proceedings of the 2023 Conference on Empirical Methods in Natural Language Processing, pages 14414–14445, Singapore. Association for Computational Linguistics.
Cite (Informal):
Exploring the Boundaries of GPT-4 in Radiology (Liu et al., EMNLP 2023)
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PDF:
https://aclanthology.org/2023.emnlp-main.891.pdf
Video:
 https://aclanthology.org/2023.emnlp-main.891.mp4