MedAgents: Large Language Models as Collaborators for Zero-shot Medical Reasoning

Xiangru Tang, Anni Zou, Zhuosheng Zhang, Ziming Li, Yilun Zhao, Xingyao Zhang, Arman Cohan, Mark Gerstein


Abstract
Large language models (LLMs), despite their remarkable progress across various general domains, encounter significant barriers in medicine and healthcare. This field faces unique challenges such as domain-specific terminologies and reasoning over specialized knowledge. To address these issues, we propose MedAgents, a novel multi-disciplinary collaboration framework for the medical domain. MedAgents leverages LLM-based agents in a role-playing setting that participate in a collaborative multi-round discussion, thereby enhancing LLM proficiency and reasoning capabilities. This training-free framework encompasses five critical steps: gathering domain experts, proposing individual analyses, summarising these analyses into a report, iterating over discussions until a consensus is reached, and ultimately making a decision. Our work focuses on the zero-shot setting, which is applicable in real-world scenarios. Experimental results on nine datasets (MedQA, MedMCQA, PubMedQA, and six subtasks from MMLU) establish that our proposed MedAgents framework excels at mining and harnessing the medical expertise within LLMs, as well as extending its reasoning abilities. Our code can be found at https://github.com/gersteinlab/MedAgents.
Anthology ID:
2024.findings-acl.33
Volume:
Findings of the Association for Computational Linguistics ACL 2024
Month:
August
Year:
2024
Address:
Bangkok, Thailand and virtual meeting
Editors:
Lun-Wei Ku, Andre Martins, Vivek Srikumar
Venue:
Findings
SIG:
Publisher:
Association for Computational Linguistics
Note:
Pages:
599–621
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URL:
https://aclanthology.org/2024.findings-acl.33
DOI:
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Cite (ACL):
Xiangru Tang, Anni Zou, Zhuosheng Zhang, Ziming Li, Yilun Zhao, Xingyao Zhang, Arman Cohan, and Mark Gerstein. 2024. MedAgents: Large Language Models as Collaborators for Zero-shot Medical Reasoning. In Findings of the Association for Computational Linguistics ACL 2024, pages 599–621, Bangkok, Thailand and virtual meeting. Association for Computational Linguistics.
Cite (Informal):
MedAgents: Large Language Models as Collaborators for Zero-shot Medical Reasoning (Tang et al., Findings 2024)
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PDF:
https://aclanthology.org/2024.findings-acl.33.pdf