@inproceedings{wu-etal-2025-medical,
title = "Medical Graph {RAG}: Evidence-based Medical Large Language Model via Graph Retrieval-Augmented Generation",
author = "Wu, Junde and
Zhu, Jiayuan and
Qi, Yunli and
Chen, Jingkun and
Xu, Min and
Menolascina, Filippo and
Jin, Yueming and
Grau, Vicente",
editor = "Che, Wanxiang and
Nabende, Joyce and
Shutova, Ekaterina and
Pilehvar, Mohammad Taher",
booktitle = "Proceedings of the 63rd Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers)",
month = jul,
year = "2025",
address = "Vienna, Austria",
publisher = "Association for Computational Linguistics",
url = "https://aclanthology.org/2025.acl-long.1381/",
doi = "10.18653/v1/2025.acl-long.1381",
pages = "28443--28467",
ISBN = "979-8-89176-251-0",
abstract = "We introduce MedGraphRAG, a novel graph-based Retrieval-Augmented Generation (RAG) framework designed to enhance LLMs in generating evidence-based medical responses, improving safety and reliability with private medical data. We introduce Triple Graph Construction and U-Retrieval to enhance GraphRAG, enabling holistic insights and evidence-based response generation for medical applications. Specifically, we connect user documents to credible medical sources and integrate Top-down Precise Retrieval with Bottom-up Response Refinement for balanced context awareness and precise indexing. Validated on 9 medical Q{\&}A benchmarks, 2 health fact-checking datasets, and a long-form generation test set, MedGraphRAG outperforms state-of-the-art models while ensuring credible sourcing. Our code is publicly available."
}<?xml version="1.0" encoding="UTF-8"?>
<modsCollection xmlns="http://www.loc.gov/mods/v3">
<mods ID="wu-etal-2025-medical">
<titleInfo>
<title>Medical Graph RAG: Evidence-based Medical Large Language Model via Graph Retrieval-Augmented Generation</title>
</titleInfo>
<name type="personal">
<namePart type="given">Junde</namePart>
<namePart type="family">Wu</namePart>
<role>
<roleTerm authority="marcrelator" type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Jiayuan</namePart>
<namePart type="family">Zhu</namePart>
<role>
<roleTerm authority="marcrelator" type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Yunli</namePart>
<namePart type="family">Qi</namePart>
<role>
<roleTerm authority="marcrelator" type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Jingkun</namePart>
<namePart type="family">Chen</namePart>
<role>
<roleTerm authority="marcrelator" type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Min</namePart>
<namePart type="family">Xu</namePart>
<role>
<roleTerm authority="marcrelator" type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Filippo</namePart>
<namePart type="family">Menolascina</namePart>
<role>
<roleTerm authority="marcrelator" type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Yueming</namePart>
<namePart type="family">Jin</namePart>
<role>
<roleTerm authority="marcrelator" type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Vicente</namePart>
<namePart type="family">Grau</namePart>
<role>
<roleTerm authority="marcrelator" type="text">author</roleTerm>
</role>
</name>
<originInfo>
<dateIssued>2025-07</dateIssued>
</originInfo>
<typeOfResource>text</typeOfResource>
<relatedItem type="host">
<titleInfo>
<title>Proceedings of the 63rd Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers)</title>
</titleInfo>
<name type="personal">
<namePart type="given">Wanxiang</namePart>
<namePart type="family">Che</namePart>
<role>
<roleTerm authority="marcrelator" type="text">editor</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Joyce</namePart>
<namePart type="family">Nabende</namePart>
<role>
<roleTerm authority="marcrelator" type="text">editor</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Ekaterina</namePart>
<namePart type="family">Shutova</namePart>
<role>
<roleTerm authority="marcrelator" type="text">editor</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Mohammad</namePart>
<namePart type="given">Taher</namePart>
<namePart type="family">Pilehvar</namePart>
<role>
<roleTerm authority="marcrelator" type="text">editor</roleTerm>
</role>
</name>
<originInfo>
<publisher>Association for Computational Linguistics</publisher>
<place>
<placeTerm type="text">Vienna, Austria</placeTerm>
</place>
</originInfo>
<genre authority="marcgt">conference publication</genre>
<identifier type="isbn">979-8-89176-251-0</identifier>
</relatedItem>
<abstract>We introduce MedGraphRAG, a novel graph-based Retrieval-Augmented Generation (RAG) framework designed to enhance LLMs in generating evidence-based medical responses, improving safety and reliability with private medical data. We introduce Triple Graph Construction and U-Retrieval to enhance GraphRAG, enabling holistic insights and evidence-based response generation for medical applications. Specifically, we connect user documents to credible medical sources and integrate Top-down Precise Retrieval with Bottom-up Response Refinement for balanced context awareness and precise indexing. Validated on 9 medical Q&A benchmarks, 2 health fact-checking datasets, and a long-form generation test set, MedGraphRAG outperforms state-of-the-art models while ensuring credible sourcing. Our code is publicly available.</abstract>
<identifier type="citekey">wu-etal-2025-medical</identifier>
<identifier type="doi">10.18653/v1/2025.acl-long.1381</identifier>
<location>
<url>https://aclanthology.org/2025.acl-long.1381/</url>
</location>
<part>
<date>2025-07</date>
<extent unit="page">
<start>28443</start>
<end>28467</end>
</extent>
</part>
</mods>
</modsCollection>
%0 Conference Proceedings
%T Medical Graph RAG: Evidence-based Medical Large Language Model via Graph Retrieval-Augmented Generation
%A Wu, Junde
%A Zhu, Jiayuan
%A Qi, Yunli
%A Chen, Jingkun
%A Xu, Min
%A Menolascina, Filippo
%A Jin, Yueming
%A Grau, Vicente
%Y Che, Wanxiang
%Y Nabende, Joyce
%Y Shutova, Ekaterina
%Y Pilehvar, Mohammad Taher
%S Proceedings of the 63rd Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers)
%D 2025
%8 July
%I Association for Computational Linguistics
%C Vienna, Austria
%@ 979-8-89176-251-0
%F wu-etal-2025-medical
%X We introduce MedGraphRAG, a novel graph-based Retrieval-Augmented Generation (RAG) framework designed to enhance LLMs in generating evidence-based medical responses, improving safety and reliability with private medical data. We introduce Triple Graph Construction and U-Retrieval to enhance GraphRAG, enabling holistic insights and evidence-based response generation for medical applications. Specifically, we connect user documents to credible medical sources and integrate Top-down Precise Retrieval with Bottom-up Response Refinement for balanced context awareness and precise indexing. Validated on 9 medical Q&A benchmarks, 2 health fact-checking datasets, and a long-form generation test set, MedGraphRAG outperforms state-of-the-art models while ensuring credible sourcing. Our code is publicly available.
%R 10.18653/v1/2025.acl-long.1381
%U https://aclanthology.org/2025.acl-long.1381/
%U https://doi.org/10.18653/v1/2025.acl-long.1381
%P 28443-28467
Markdown (Informal)
[Medical Graph RAG: Evidence-based Medical Large Language Model via Graph Retrieval-Augmented Generation](https://aclanthology.org/2025.acl-long.1381/) (Wu et al., ACL 2025)
ACL
- Junde Wu, Jiayuan Zhu, Yunli Qi, Jingkun Chen, Min Xu, Filippo Menolascina, Yueming Jin, and Vicente Grau. 2025. Medical Graph RAG: Evidence-based Medical Large Language Model via Graph Retrieval-Augmented Generation. In Proceedings of the 63rd Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers), pages 28443–28467, Vienna, Austria. Association for Computational Linguistics.