Team MonoLink at the ALTA Shared Task 2025: Synonym-Aware Retrieval with Guideline-Aware Re-Ranking for MedDRA Normalization

James C. Douglas


Abstract
We describe Team MonoLink’s system for the ALTA 2025 Shared Task on normalizing patient-authored adverse drug event (ADE) mentions to MedDRA Lowest Level Terms (LLTs). Our pipeline combines recall-oriented, synonym-augmented candidate retrieval with cross-encoder re-ranking and a guideline-aware LLM discriminator. On the official hidden test set, our submission tied for first place, achieving an Accuracy@1 of 39.8%, Accuracy@5 of 78.3%, and Accuracy@10 of 85.5%.
Anthology ID:
2025.alta-main.15
Volume:
Proceedings of the 23rd Annual Workshop of the Australasian Language Technology Association
Month:
November
Year:
2025
Address:
Sydney, Australia
Editors:
Jonathan K. Kummerfeld, Aditya Joshi, Mark Dras
Venues:
ALTA | WS
SIG:
Publisher:
Association for Computational Linguistics
Note:
Pages:
208–215
Language:
URL:
https://aclanthology.org/2025.alta-main.15/
DOI:
Bibkey:
Cite (ACL):
James C. Douglas. 2025. Team MonoLink at the ALTA Shared Task 2025: Synonym-Aware Retrieval with Guideline-Aware Re-Ranking for MedDRA Normalization. In Proceedings of the 23rd Annual Workshop of the Australasian Language Technology Association, pages 208–215, Sydney, Australia. Association for Computational Linguistics.
Cite (Informal):
Team MonoLink at the ALTA Shared Task 2025: Synonym-Aware Retrieval with Guideline-Aware Re-Ranking for MedDRA Normalization (Douglas, ALTA 2025)
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PDF:
https://aclanthology.org/2025.alta-main.15.pdf