PIRsuader: A Persuasive Chatbot for Mitigating Psychological Insulin Resistance in Type-2 Diabetic Patients

Sujatha Das Gollapalli, See-Kiong Ng


Abstract
Psychological Insulin Resistance (PIR) is described as the reluctance towards initiation and adherence of insulin-based treatments due to psychological barriers in diabetic patients. Though studies have shown that timely initiation with lifestyle changes are known to be crucial in sugar control and prevention of chronic conditions in Type 2 Diabetes (T2D) patients, many patients often have deep-rooted fears and misgivings related to insulin which hinder them from adapting to an insulin-based treatment regimen when recommended by healthcare specialists. Therefore, it is vitally important to address and allay these fallacious beliefs in T2D patients and persuade them to consider insulin as a treatment option. In this paper, we describe the design of PIRsuader, a persuasive chatbot for mitigating PIR in T2D patients. In PIRsuader, we effectively harness the conversation generation capabilities of state-of-the-art Large Language Models via a context-specific persuasive dialog act schema. We design reward functions that capture dialog act preferences for persuading reluctant patients and apply reinforcement learning to learn a dialog act prediction model. Our experiments using a collection of real doctor-diabetic patient conversations indicate that PIRsuader is able to improve the willingness in patients to try insulin as well as address specific concerns they have in an empathetic manner.
Anthology ID:
2025.coling-main.401
Volume:
Proceedings of the 31st International Conference on Computational Linguistics
Month:
January
Year:
2025
Address:
Abu Dhabi, UAE
Editors:
Owen Rambow, Leo Wanner, Marianna Apidianaki, Hend Al-Khalifa, Barbara Di Eugenio, Steven Schockaert
Venue:
COLING
SIG:
Publisher:
Association for Computational Linguistics
Note:
Pages:
5997–6013
Language:
URL:
https://aclanthology.org/2025.coling-main.401/
DOI:
Bibkey:
Cite (ACL):
Sujatha Das Gollapalli and See-Kiong Ng. 2025. PIRsuader: A Persuasive Chatbot for Mitigating Psychological Insulin Resistance in Type-2 Diabetic Patients. In Proceedings of the 31st International Conference on Computational Linguistics, pages 5997–6013, Abu Dhabi, UAE. Association for Computational Linguistics.
Cite (Informal):
PIRsuader: A Persuasive Chatbot for Mitigating Psychological Insulin Resistance in Type-2 Diabetic Patients (Gollapalli & Ng, COLING 2025)
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PDF:
https://aclanthology.org/2025.coling-main.401.pdf