@inproceedings{qi-etal-2025-metascientist,
title = "{M}eta{S}cientist: A Human-{AI} Synergistic Framework for Automated Mechanical Metamaterial Design",
author = "Qi, Jingyuan and
Jia, Zian and
Liu, Minqian and
Zhan, Wangzhi and
Zhang, Junkai and
Wen, Xiaofei and
Gan, Jingru and
Chen, Jianpeng and
Liu, Qin and
Ma, Mingyu Derek and
Li, Bangzheng and
Wang, Haohui and
Kulkarni, Adithya and
Chen, Muhao and
Zhou, Dawei and
Li, Ling and
Wang, Wei and
Huang, Lifu",
editor = "Dziri, Nouha and
Ren, Sean (Xiang) and
Diao, Shizhe",
booktitle = "Proceedings of the 2025 Conference of the Nations of the Americas Chapter of the Association for Computational Linguistics: Human Language Technologies (System Demonstrations)",
month = apr,
year = "2025",
address = "Albuquerque, New Mexico",
publisher = "Association for Computational Linguistics",
url = "https://aclanthology.org/2025.naacl-demo.34/",
doi = "10.18653/v1/2025.naacl-demo.34",
pages = "404--436",
ISBN = "979-8-89176-191-9",
abstract = "The discovery of novel mechanical metamaterials, whose properties are dominated by their engineered structures rather than chemical composition, is a knowledge-intensive and resource-demanding process. To accelerate the design of novel metamaterials, we present MetaScientist, a human-in-the-loop system that integrates advanced AI capabilities with expert oversight with two primary phases: (1) hypothesis generation, where the system performs complex reasoning to generate novel and scientifically sound hypotheses, supported with domain-specific foundation models and inductive biases retrieved from existing literature; (2) 3D structure synthesis, where a 3D structure is synthesized with a novel 3D diffusion model based on the textual hypothesis and refined it with a LLM-based refinement model to achieve better structure properties. At each phase, domain experts iteratively validate the system outputs, and provide feedback and supplementary materials to ensure the alignment of the outputs with scientific principles and human preferences. Through extensive evaluation from human scientists, MetaScientist is able to deliver novel and valid mechanical metamaterial designs that have the potential to be highly impactful in the metamaterial field."
}<?xml version="1.0" encoding="UTF-8"?>
<modsCollection xmlns="http://www.loc.gov/mods/v3">
<mods ID="qi-etal-2025-metascientist">
<titleInfo>
<title>MetaScientist: A Human-AI Synergistic Framework for Automated Mechanical Metamaterial Design</title>
</titleInfo>
<name type="personal">
<namePart type="given">Jingyuan</namePart>
<namePart type="family">Qi</namePart>
<role>
<roleTerm authority="marcrelator" type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Zian</namePart>
<namePart type="family">Jia</namePart>
<role>
<roleTerm authority="marcrelator" type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Minqian</namePart>
<namePart type="family">Liu</namePart>
<role>
<roleTerm authority="marcrelator" type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Wangzhi</namePart>
<namePart type="family">Zhan</namePart>
<role>
<roleTerm authority="marcrelator" type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Junkai</namePart>
<namePart type="family">Zhang</namePart>
<role>
<roleTerm authority="marcrelator" type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Xiaofei</namePart>
<namePart type="family">Wen</namePart>
<role>
<roleTerm authority="marcrelator" type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Jingru</namePart>
<namePart type="family">Gan</namePart>
<role>
<roleTerm authority="marcrelator" type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Jianpeng</namePart>
<namePart type="family">Chen</namePart>
<role>
<roleTerm authority="marcrelator" type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Qin</namePart>
<namePart type="family">Liu</namePart>
<role>
<roleTerm authority="marcrelator" type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Mingyu</namePart>
<namePart type="given">Derek</namePart>
<namePart type="family">Ma</namePart>
<role>
<roleTerm authority="marcrelator" type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Bangzheng</namePart>
<namePart type="family">Li</namePart>
<role>
<roleTerm authority="marcrelator" type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Haohui</namePart>
<namePart type="family">Wang</namePart>
<role>
<roleTerm authority="marcrelator" type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Adithya</namePart>
<namePart type="family">Kulkarni</namePart>
<role>
<roleTerm authority="marcrelator" type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Muhao</namePart>
<namePart type="family">Chen</namePart>
<role>
<roleTerm authority="marcrelator" type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Dawei</namePart>
<namePart type="family">Zhou</namePart>
<role>
<roleTerm authority="marcrelator" type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Ling</namePart>
<namePart type="family">Li</namePart>
<role>
<roleTerm authority="marcrelator" type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Wei</namePart>
<namePart type="family">Wang</namePart>
<role>
<roleTerm authority="marcrelator" type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Lifu</namePart>
<namePart type="family">Huang</namePart>
<role>
<roleTerm authority="marcrelator" type="text">author</roleTerm>
</role>
</name>
<originInfo>
<dateIssued>2025-04</dateIssued>
</originInfo>
<typeOfResource>text</typeOfResource>
<relatedItem type="host">
<titleInfo>
<title>Proceedings of the 2025 Conference of the Nations of the Americas Chapter of the Association for Computational Linguistics: Human Language Technologies (System Demonstrations)</title>
</titleInfo>
<name type="personal">
<namePart type="given">Nouha</namePart>
<namePart type="family">Dziri</namePart>
<role>
<roleTerm authority="marcrelator" type="text">editor</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Sean</namePart>
<namePart type="given">(Xiang)</namePart>
<namePart type="family">Ren</namePart>
<role>
<roleTerm authority="marcrelator" type="text">editor</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Shizhe</namePart>
<namePart type="family">Diao</namePart>
<role>
<roleTerm authority="marcrelator" type="text">editor</roleTerm>
</role>
</name>
<originInfo>
<publisher>Association for Computational Linguistics</publisher>
<place>
<placeTerm type="text">Albuquerque, New Mexico</placeTerm>
</place>
</originInfo>
<genre authority="marcgt">conference publication</genre>
<identifier type="isbn">979-8-89176-191-9</identifier>
</relatedItem>
<abstract>The discovery of novel mechanical metamaterials, whose properties are dominated by their engineered structures rather than chemical composition, is a knowledge-intensive and resource-demanding process. To accelerate the design of novel metamaterials, we present MetaScientist, a human-in-the-loop system that integrates advanced AI capabilities with expert oversight with two primary phases: (1) hypothesis generation, where the system performs complex reasoning to generate novel and scientifically sound hypotheses, supported with domain-specific foundation models and inductive biases retrieved from existing literature; (2) 3D structure synthesis, where a 3D structure is synthesized with a novel 3D diffusion model based on the textual hypothesis and refined it with a LLM-based refinement model to achieve better structure properties. At each phase, domain experts iteratively validate the system outputs, and provide feedback and supplementary materials to ensure the alignment of the outputs with scientific principles and human preferences. Through extensive evaluation from human scientists, MetaScientist is able to deliver novel and valid mechanical metamaterial designs that have the potential to be highly impactful in the metamaterial field.</abstract>
<identifier type="citekey">qi-etal-2025-metascientist</identifier>
<identifier type="doi">10.18653/v1/2025.naacl-demo.34</identifier>
<location>
<url>https://aclanthology.org/2025.naacl-demo.34/</url>
</location>
<part>
<date>2025-04</date>
<extent unit="page">
<start>404</start>
<end>436</end>
</extent>
</part>
</mods>
</modsCollection>
%0 Conference Proceedings
%T MetaScientist: A Human-AI Synergistic Framework for Automated Mechanical Metamaterial Design
%A Qi, Jingyuan
%A Jia, Zian
%A Liu, Minqian
%A Zhan, Wangzhi
%A Zhang, Junkai
%A Wen, Xiaofei
%A Gan, Jingru
%A Chen, Jianpeng
%A Liu, Qin
%A Ma, Mingyu Derek
%A Li, Bangzheng
%A Wang, Haohui
%A Kulkarni, Adithya
%A Chen, Muhao
%A Zhou, Dawei
%A Li, Ling
%A Wang, Wei
%A Huang, Lifu
%Y Dziri, Nouha
%Y Ren, Sean (Xiang)
%Y Diao, Shizhe
%S Proceedings of the 2025 Conference of the Nations of the Americas Chapter of the Association for Computational Linguistics: Human Language Technologies (System Demonstrations)
%D 2025
%8 April
%I Association for Computational Linguistics
%C Albuquerque, New Mexico
%@ 979-8-89176-191-9
%F qi-etal-2025-metascientist
%X The discovery of novel mechanical metamaterials, whose properties are dominated by their engineered structures rather than chemical composition, is a knowledge-intensive and resource-demanding process. To accelerate the design of novel metamaterials, we present MetaScientist, a human-in-the-loop system that integrates advanced AI capabilities with expert oversight with two primary phases: (1) hypothesis generation, where the system performs complex reasoning to generate novel and scientifically sound hypotheses, supported with domain-specific foundation models and inductive biases retrieved from existing literature; (2) 3D structure synthesis, where a 3D structure is synthesized with a novel 3D diffusion model based on the textual hypothesis and refined it with a LLM-based refinement model to achieve better structure properties. At each phase, domain experts iteratively validate the system outputs, and provide feedback and supplementary materials to ensure the alignment of the outputs with scientific principles and human preferences. Through extensive evaluation from human scientists, MetaScientist is able to deliver novel and valid mechanical metamaterial designs that have the potential to be highly impactful in the metamaterial field.
%R 10.18653/v1/2025.naacl-demo.34
%U https://aclanthology.org/2025.naacl-demo.34/
%U https://doi.org/10.18653/v1/2025.naacl-demo.34
%P 404-436
Markdown (Informal)
[MetaScientist: A Human-AI Synergistic Framework for Automated Mechanical Metamaterial Design](https://aclanthology.org/2025.naacl-demo.34/) (Qi et al., NAACL 2025)
ACL
- Jingyuan Qi, Zian Jia, Minqian Liu, Wangzhi Zhan, Junkai Zhang, Xiaofei Wen, Jingru Gan, Jianpeng Chen, Qin Liu, Mingyu Derek Ma, Bangzheng Li, Haohui Wang, Adithya Kulkarni, Muhao Chen, Dawei Zhou, Ling Li, Wei Wang, and Lifu Huang. 2025. MetaScientist: A Human-AI Synergistic Framework for Automated Mechanical Metamaterial Design. In Proceedings of the 2025 Conference of the Nations of the Americas Chapter of the Association for Computational Linguistics: Human Language Technologies (System Demonstrations), pages 404–436, Albuquerque, New Mexico. Association for Computational Linguistics.