@inproceedings{hogan-shang-2025-entangled,
title = "Entangled Relations: Leveraging {NLI} and Meta-analysis to Enhance Biomedical Relation Extraction",
author = "Hogan, William P and
Shang, Jingbo",
editor = "Chiruzzo, Luis and
Ritter, Alan and
Wang, Lu",
booktitle = "Proceedings of the 2025 Conference of the Nations of the Americas Chapter of the Association for Computational Linguistics: Human Language Technologies (Volume 1: Long Papers)",
month = apr,
year = "2025",
address = "Albuquerque, New Mexico",
publisher = "Association for Computational Linguistics",
url = "https://aclanthology.org/2025.naacl-long.165/",
doi = "10.18653/v1/2025.naacl-long.165",
pages = "3204--3220",
ISBN = "979-8-89176-189-6",
abstract = "Recent research efforts have explored the potential of leveraging natural language inference (NLI) techniques to enhance relation extraction (RE). In this vein, we introduce MetaEntail-RE, a novel adaptation method that harnesses NLI principles to enhance RE performance. Our approach follows past works by verbalizing relation classes into class-indicative hypotheses, aligning a traditionally multi-class classification task to one of textual entailment. We introduce three key enhancements: (1) Meta-class analysis which, instead of labeling non-entailed premise-hypothesis pairs with the less informative ``neutral'' entailment label, provides additional context by analyzing overarching meta-relationships between classes; (2) Feasible hypothesis filtering, which removes unlikely hypotheses from consideration based on domain knowledge derived from data; and (3) Group-based prediction selection, which further improves performance by selecting highly confident predictions. MetaEntail-RE is conceptually simple and empirically powerful, yielding significant improvements over conventional relation extraction techniques and other NLI formulations. We observe surprisingly large F1 gains of 17.6 points on BioRED and 13.4 points on ReTACRED compared to conventional methods, underscoring the versatility of MetaEntail-RE across both biomedical and general domains."
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<abstract>Recent research efforts have explored the potential of leveraging natural language inference (NLI) techniques to enhance relation extraction (RE). In this vein, we introduce MetaEntail-RE, a novel adaptation method that harnesses NLI principles to enhance RE performance. Our approach follows past works by verbalizing relation classes into class-indicative hypotheses, aligning a traditionally multi-class classification task to one of textual entailment. We introduce three key enhancements: (1) Meta-class analysis which, instead of labeling non-entailed premise-hypothesis pairs with the less informative “neutral” entailment label, provides additional context by analyzing overarching meta-relationships between classes; (2) Feasible hypothesis filtering, which removes unlikely hypotheses from consideration based on domain knowledge derived from data; and (3) Group-based prediction selection, which further improves performance by selecting highly confident predictions. MetaEntail-RE is conceptually simple and empirically powerful, yielding significant improvements over conventional relation extraction techniques and other NLI formulations. We observe surprisingly large F1 gains of 17.6 points on BioRED and 13.4 points on ReTACRED compared to conventional methods, underscoring the versatility of MetaEntail-RE across both biomedical and general domains.</abstract>
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%0 Conference Proceedings
%T Entangled Relations: Leveraging NLI and Meta-analysis to Enhance Biomedical Relation Extraction
%A Hogan, William P.
%A Shang, Jingbo
%Y Chiruzzo, Luis
%Y Ritter, Alan
%Y Wang, Lu
%S Proceedings of the 2025 Conference of the Nations of the Americas Chapter of the Association for Computational Linguistics: Human Language Technologies (Volume 1: Long Papers)
%D 2025
%8 April
%I Association for Computational Linguistics
%C Albuquerque, New Mexico
%@ 979-8-89176-189-6
%F hogan-shang-2025-entangled
%X Recent research efforts have explored the potential of leveraging natural language inference (NLI) techniques to enhance relation extraction (RE). In this vein, we introduce MetaEntail-RE, a novel adaptation method that harnesses NLI principles to enhance RE performance. Our approach follows past works by verbalizing relation classes into class-indicative hypotheses, aligning a traditionally multi-class classification task to one of textual entailment. We introduce three key enhancements: (1) Meta-class analysis which, instead of labeling non-entailed premise-hypothesis pairs with the less informative “neutral” entailment label, provides additional context by analyzing overarching meta-relationships between classes; (2) Feasible hypothesis filtering, which removes unlikely hypotheses from consideration based on domain knowledge derived from data; and (3) Group-based prediction selection, which further improves performance by selecting highly confident predictions. MetaEntail-RE is conceptually simple and empirically powerful, yielding significant improvements over conventional relation extraction techniques and other NLI formulations. We observe surprisingly large F1 gains of 17.6 points on BioRED and 13.4 points on ReTACRED compared to conventional methods, underscoring the versatility of MetaEntail-RE across both biomedical and general domains.
%R 10.18653/v1/2025.naacl-long.165
%U https://aclanthology.org/2025.naacl-long.165/
%U https://doi.org/10.18653/v1/2025.naacl-long.165
%P 3204-3220
Markdown (Informal)
[Entangled Relations: Leveraging NLI and Meta-analysis to Enhance Biomedical Relation Extraction](https://aclanthology.org/2025.naacl-long.165/) (Hogan & Shang, NAACL 2025)
ACL