HARPA: A Testability-Driven, Literature-Grounded Framework for Research Ideation

Rosni Vasu, Peter Jansen, Pao Siangliulue, Cristina Sarasua, Abraham Bernstein, Peter Clark, Bhavana Dalvi Mishra


Abstract
Recent advances in large language models (LLMs) have accelerated automated scientific discovery (ASD), but existing ideation tools still struggle to generate hypotheses that are both testable, literature-grounded, and adaptive to prior experimental outcomes. We developed HARPA to address these challenges by following a human-inspired ideation workflow that mines literature trends, explores hypothesis design spaces, and converges on precise, testable hypotheses by pinpointing research gaps and justifying design choices. Human evaluations show that HARPA-generated hypothesis-driven research proposals performs comparably to a strong baseline system, AI-researcher, in novelty and overall quality, while showing a positive trend in feasibility (+0.78, p<0.05, bootstrap) and a significant gain in groundedness (+0.85, p<0.01, bootstrap) on a 10-point Likert scale. When evaluated with the ASD agent CodeScientist, HARPA produced more successful executions (20 vs. 11 out of 40) and fewer failures (16 vs. 21 out of 40) indicating that expert feasibility judgments track execution success. HARPA also learns a reward model that scores hypotheses based on prior experimental outcomes, achieving approx. a 28% absolute gain over HARPA’s untrained baseline scorer.
Anthology ID:
2026.aacl-long.215
Volume:
Proceedings of the 15th International Joint Conference on Natural Language Processing and the 5th Conference of the Asia-Pacific Chapter of the Association for Computational Linguistics (Volume 1: Long Papers)
Month:
November
Year:
2026
Address:
Hengqin, China
Editors:
Yue Zhang, Ruifeng Xu, Ayu Purwarianti, Tong Rong, Jun Suzuki
Venues:
AACL | IJCNLP
SIG:
Publisher:
Association for Computational Linguistics
Note:
Pages:
4821–4880
Language:
URL:
https://aclanthology.org/2026.aacl-long.215/
DOI:
Bibkey:
Cite (ACL):
Rosni Vasu, Peter Jansen, Pao Siangliulue, Cristina Sarasua, Abraham Bernstein, Peter Clark, and Bhavana Dalvi Mishra. 2026. HARPA: A Testability-Driven, Literature-Grounded Framework for Research Ideation. In Proceedings of the 15th International Joint Conference on Natural Language Processing and the 5th Conference of the Asia-Pacific Chapter of the Association for Computational Linguistics (Volume 1: Long Papers), pages 4821–4880, Hengqin, China. Association for Computational Linguistics.
Cite (Informal):
HARPA: A Testability-Driven, Literature-Grounded Framework for Research Ideation (Vasu et al., AACL-IJCNLP 2026)
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PDF:
https://aclanthology.org/2026.aacl-long.215.pdf