Datasets for a Chatbot for Clinical Trial Search

Yumeng Yang, Ethan Ludmir, Kirk Roberts


Abstract
Matching patients to clinical trials is a critical bottleneck hindered by complex eligibility criteria. While conversational AI offers a promising solution, its safe deployment depends on high-quality, domain specific data. This paper introduces three benchmark datasets designed to support the development and evaluation of conversational agents for clinical trial pre-screening. First, a manually-annotated paired-criterion dataset provides a gold standard for structuring raw criteria, which we used to objectively group 12,596 criteria. Second, we curated a human-authored question benchmark to validate the clinical fidelity and patient-centric clarity of questions generated by a medical LLM, ensuring the AI’s dialogue is accurate and understandable. Third, we constructed a human-validated assessment corpus of criterion-question-answer tuples with human-labeled outcomes to evaluate criterion classification based on a patient’s answer to a generated question. The primary contribution of this work is a foundational set of benchmark datasets, designed to support and evaluate key components for a chatbot for clinical trial search.
Anthology ID:
2026.cl4health-1.13
Volume:
Proceedings of the Third Workshop on Patient-Oriented Language Processing (CL4Health) @ LREC 2026
Month:
May
Year:
2026
Address:
Palma, Mallorca (Spain)
Editors:
Deepak Gupta, Paul Thompson, Sophia Ananiadou, Dina Demner-Fushman
Venues:
CL4Health | WS
SIG:
Publisher:
ELRA Language Resources Association (ELRA)
Note:
Pages:
139–148
Language:
External URL:
https://lrec.elra.info/lrec2026-ws-cl4health-13
DOI:
10.63317/3pk9cracmxy7
Bibkey:
Cite (ACL):
Yumeng Yang, Ethan Ludmir, and Kirk Roberts. 2026. Datasets for a Chatbot for Clinical Trial Search. In Proceedings of the Third Workshop on Patient-Oriented Language Processing (CL4Health) @ LREC 2026, pages 139–148, Palma, Mallorca (Spain). ELRA Language Resources Association (ELRA).
Cite (Informal):
Datasets for a Chatbot for Clinical Trial Search (Yang et al., CL4Health 2026)
Copy Citation: