Reasoning, Contrastive, and In-Context Strategies for Opioid Use Stage Detection on Social Media

Vinu Ekanayake, Ramakanth Kavuluru


Abstract
The opioid epidemic has ravaged the US for the past two decades and is still a persistent threat. During the same time, the increasing use of social media has created a new avenue for people to share their journeys regarding opioid use. In this context, research in automatically determining opioid use stages (e.g., misuse, addiction, recovery) based on self disclosures in social media posts is gaining traction. In this paper, using a recent benchmark, we assess different supervised strategies for identifying self-disclosed opioid use stages from Reddit posts. We consider distilled reasoning traces from DeepSeek R1 (an open weights reasoning model), supervised contrastive learning (SCL), and few-shot in-context learning (ICL) with GPT-5 to conduct a variety of experiments with encoder and encoder-decoder models. We also conduct direct zero-shot (ZS) experiments with GPT 5 and GPT 5.2. Across different models and datasets, our strategies provide improvements in performance with some nuances that are too subtle to elaborate in the abstract. A surprising finding is that ZS results with GPT-5 are better than all supervised results, which ushers a new frontier for LLM-based classification of opioid use in social media posts. Our code is available for reuse and replication: https://github.com/bionlproc/Opioid-Stage.
Anthology ID:
2026.cl4health-1.19
Volume:
Proceedings of the Third Workshop on Patient-Oriented Language Processing (CL4Health) @ LREC 2026
Month:
May
Year:
2026
Address:
Palma, Mallorca (Spain)
Editors:
Deepak Gupta, Paul Thompson, Sophia Ananiadou, Dina Demner-Fushman
Venues:
CL4Health | WS
SIG:
Publisher:
ELRA Language Resources Association (ELRA)
Note:
Pages:
207–222
Language:
External URL:
https://lrec.elra.info/lrec2026-ws-cl4health-19
DOI:
10.63317/4eyh8vc3atun
Bibkey:
Cite (ACL):
Vinu Ekanayake and Ramakanth Kavuluru. 2026. Reasoning, Contrastive, and In-Context Strategies for Opioid Use Stage Detection on Social Media. In Proceedings of the Third Workshop on Patient-Oriented Language Processing (CL4Health) @ LREC 2026, pages 207–222, Palma, Mallorca (Spain). ELRA Language Resources Association (ELRA).
Cite (Informal):
Reasoning, Contrastive, and In-Context Strategies for Opioid Use Stage Detection on Social Media (Ekanayake & Kavuluru, CL4Health 2026)
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