Differentially Private De-identification of Dutch Clinical Notes: A Comparative Evaluation

Michele Miranda, Xinlan Yan, Nishant Mishra, Rachel Murphy, Ameen Abu Hanna, Sébastien Bratières, Iacer Calixto


Abstract
Protecting patient privacy in clinical narratives is essential for enabling secondary use of healthcare data under regulations such as GDPR and HIPAA. While manual de-identification remains the gold standard, it is costly and slow, motivating the need for automated methods that combine privacy guarantees with high utility. Historically, most automated text de-identification pipelines employed named entity recognition (NER) to identify protected entities for redaction. Although methods based on differential privacy (DP) provide formal privacy guarantees, more recently also large language models (LLMs) are increasingly used for text de-identification in the clinical domain. In this work, we present the first comparative study of DP, NER, and LLMs for Dutch clinical text de-identification. We investigate these methods separately as well as hybrid strategies that apply NER or LLM preprocessing prior to DP, and assess performance in terms of privacy leakage and extrinsic evaluation (entity and relation classification). We show that DP mechanisms alone degrade utility substantially, but combining them with linguistic preprocessing, especially LLM-based redaction, significantly improves the privacy–utility trade-off.
Anthology ID:
2026.clinicalnlp-1.13
Volume:
Proceedings of the 8th Workshop on Clinical Natural Language Processing (Clinical NLP) @ LREC 2026
Month:
May
Year:
2026
Address:
Palma, Mallorca (Spain)
Editors:
Asma Ben Abacha, Steven Bethard, Danielle Bitterman, Tristan Naumann, Kirk Roberts
Venues:
ClinicalNLP | WS
SIG:
Publisher:
ELRA Language Resources Association (ELRA)
Note:
Pages:
113–124
Language:
External URL:
https://lrec.elra.info/lrec2026-ws-clinicalnlp-13
DOI:
10.63317/2xrg7fmndfhy
Bibkey:
Cite (ACL):
Michele Miranda, Xinlan Yan, Nishant Mishra, Rachel Murphy, Ameen Abu Hanna, Sébastien Bratières, and Iacer Calixto. 2026. Differentially Private De-identification of Dutch Clinical Notes: A Comparative Evaluation. In Proceedings of the 8th Workshop on Clinical Natural Language Processing (Clinical NLP) @ LREC 2026, pages 113–124, Palma, Mallorca (Spain). ELRA Language Resources Association (ELRA).
Cite (Informal):
Differentially Private De-identification of Dutch Clinical Notes: A Comparative Evaluation (Miranda et al., ClinicalNLP 2026)
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