DIASENTINEL: An Auditable Multi-Agent System for Guideline-Grounded Diabetes Risk Screening

Yung Wei Shueh, Zhi-Jie Chen, Chia-Hsuan Hsu, Hsin-Ling Hsu, Donghua Zhang, Chenwei Wu, Jun-En Ding, Tongze Zhang, Shihao Yang, Pengfei Hu, Fang Ming Hung, Feng Liu


Abstract
Large language models (LLMs) offer promising clinical decision support but remain vulnerable to hallucinated facts, unsupported recommendations, and citation errors. We present DIASENTINEL, a fully on-premise multi-agent system for one-year type 2 diabetes mellitus (T2DM) risk screening and guideline-grounded report generation from electronic health records (EHRs). The system integrates calibrated risk prediction, deterministic clinical signal extraction, Reciprocal Rank Fusion over American Diabetes Association (ADA) guidelines, and a hybrid verification layer combining rule-based checks with LLM entailment. The demonstration provides a real-time batch-screening dashboard and an interactive patient report interface with cited recommendations, verification results, and raw EHR comparison. DIASENTINEL demonstrates a practical framework for reliable, auditable, and privacy-preserving LLM-based clinical decision support. Our system demonstration can be found at https://diasentinel-demo.onrender.com/
Anthology ID:
2026.emnlp-demos.32
Volume:
Proceedings of the 2026 Conference on Empirical Methods in Natural Language Processing: System Demonstrations
Month:
October
Year:
2026
Address:
Budapest, Hungary
Editors:
Sweta Agrawal, Alberto Abad
Venue:
EMNLP
SIG:
SIGDAT
Publisher:
Association for Computational Linguistics
Note:
Pages:
320–329
Language:
URL:
https://aclanthology.org/2026.emnlp-demos.32/
DOI:
Bibkey:
Cite (ACL):
Yung Wei Shueh, Zhi-Jie Chen, Chia-Hsuan Hsu, Hsin-Ling Hsu, Donghua Zhang, Chenwei Wu, Jun-En Ding, Tongze Zhang, Shihao Yang, Pengfei Hu, Fang Ming Hung, and Feng Liu. 2026. DIASENTINEL: An Auditable Multi-Agent System for Guideline-Grounded Diabetes Risk Screening. In Proceedings of the 2026 Conference on Empirical Methods in Natural Language Processing: System Demonstrations, pages 320–329, Budapest, Hungary. Association for Computational Linguistics.
Cite (Informal):
DIASENTINEL: An Auditable Multi-Agent System for Guideline-Grounded Diabetes Risk Screening (Shueh et al., EMNLP 2026)
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PDF:
https://aclanthology.org/2026.emnlp-demos.32.pdf