MetaBench: Benchmarking Two-Stage Reranking and Top-N Screening for Meta-Analyses

Yining Huang, Keke Tang, Meilian Chen


Abstract
Meta-analyses are central to evidence-based medicine, but their production remains slow because reviewers must search PubMed and screen large candidate sets under PICOS eligibility constraints. We introduce MetaBench, a large-scale benchmark for early-stage PubMed title/abstract citation screening in meta-analysis study selection, formulated as a two-stage reranking and Top-N screening problem with effort-aware evaluation. MetaBench contains 7,801 PubMed meta-analyses, 120,930 PMID-linked included studies, and reproducible candidate pools with 4.2M unique title/abstract records constructed from replayed PubMed strategies or expert-validated training-only reconstructions. To improve evaluation fidelity, we introduce a coverage-based tiering protocol and reserve Tier 1 (1,297 topics) as a high-integrity test set. MetaBench evaluates candidate reranking with Recall/nDCG and Effort@R/NormEffort@R, and budgeted Top-N screening with sensitivity, specificity, precision, and F-scores. The main benchmark intentionally focuses on scalable title/abstract screening rather than full-text eligibility adjudication; PMCID metadata supports an auxiliary full-text track on an OA-constrained subset. Experiments show that MetaBench supervision improves dense reranking, reduces screening effort, and strengthens LLM-based inclusion decisions. An anonymized codebase and dataset sample are included with this ARR submission; the full dataset and codebase will be publicly released upon acceptance.
Anthology ID:
2026.emnlp-main.1179
Volume:
Proceedings of the 2026 Conference on Empirical Methods in Natural Language Processing
Month:
October
Year:
2026
Address:
Budapest, Hungary
Editors:
Hung-Yi Lee, Sunipa Dev, Jessy Li, Desmond Elliott
Venue:
EMNLP
SIG:
SIGDAT
Publisher:
Association for Computational Linguistics
Note:
Pages:
27010–27050
Language:
URL:
https://aclanthology.org/2026.emnlp-main.1179/
DOI:
Bibkey:
Cite (ACL):
Yining Huang, Keke Tang, and Meilian Chen. 2026. MetaBench: Benchmarking Two-Stage Reranking and Top-N Screening for Meta-Analyses. In Proceedings of the 2026 Conference on Empirical Methods in Natural Language Processing, pages 27010–27050, Budapest, Hungary. Association for Computational Linguistics.
Cite (Informal):
MetaBench: Benchmarking Two-Stage Reranking and Top-N Screening for Meta-Analyses (Huang et al., EMNLP 2026)
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PDF:
https://aclanthology.org/2026.emnlp-main.1179.pdf