FaithMed: Training LLMs For Faithful Evidence-Based Medical Reasoning

Zhiyun Zhang, Liwen Sun, Xiang Qian, Chenyan Xiong


Abstract
Faithful reasoning is essential in medicine, where clinical decisions require transparent justification grounded in reliable evidence. Current medical LLMs either lack active access to evidence or use retrieved evidence without supervising how it should be appraised and applied during reasoning. To address this, we formalize evidence-based medicine principles as process-level criteria and introduce FaithMed, a framework that combines clinician-designed, automatically refined rubrics with reinforcement learning using step-level process reward assignment and advantage grouping. Across seven medical benchmarks, FaithMed improves over agentic-search baselines (+9% on average) and outcome-only RL (+5.8%), while raising average evidence-based medicine rubric scores over agentic-search Qwen3 baselines (+15.5%). This work demonstrates that explicit step-level supervision can improve both task success and the faithfulness of the reasoning process. Code is available at https://github.com/cxcscmu/FaithMed.
Anthology ID:
2026.emnlp-main.1619
Volume:
Proceedings of the 2026 Conference on Empirical Methods in Natural Language Processing
Month:
October
Year:
2026
Address:
Budapest, Hungary
Editors:
Hung-Yi Lee, Sunipa Dev, Jessy Li, Desmond Elliott
Venue:
EMNLP
SIG:
SIGDAT
Publisher:
Association for Computational Linguistics
Note:
Pages:
36807–36822
Language:
URL:
https://aclanthology.org/2026.emnlp-main.1619/
DOI:
Bibkey:
Cite (ACL):
Zhiyun Zhang, Liwen Sun, Xiang Qian, and Chenyan Xiong. 2026. FaithMed: Training LLMs For Faithful Evidence-Based Medical Reasoning. In Proceedings of the 2026 Conference on Empirical Methods in Natural Language Processing, pages 36807–36822, Budapest, Hungary. Association for Computational Linguistics.
Cite (Informal):
FaithMed: Training LLMs For Faithful Evidence-Based Medical Reasoning (Zhang et al., EMNLP 2026)
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PDF:
https://aclanthology.org/2026.emnlp-main.1619.pdf