BioELX: Context-Aware Cross-lingual Biomedical Entity Linking without Task-Specific Supervision

Yi Wang, Corina Dima, Liangyu Zhong, Steffen Staab


Abstract
Cross-lingual biomedical entity linking (BEL) maps mentions in any language to unique identifiers in a biomedical knowledge base, supporting clinical and biomedical NLP applications. We identify two issues affecting current systems. First, the UMLS aliases used to train cross-lingual BEL retrievers are heavily skewed toward English, so retrievers generalize poorly to non-English mentions. Second, although context is often necessary for disambiguation, naively injecting context into retrievers trained only to align aliases severely degrades retrieval. We propose BioELX, a retrieve-rerank framework that addresses both issues. For retrieval, we continue training SapBERT\mbox{multi} using Wikidata-derived cross-lingual alias supervision, forming shared concept neighborhoods across languages. For reranking, we adapt pretrained LLM rerankers to entity linking through mention-anchored prompting, which marks the target mention so that rerankers score candidates with respect to the intended mention rather than other salient tokens in the context. Experiments show that BioELX achieves new state-of-the-art results on four cross-lingual BEL benchmarks, improving Recall@1 by 4.8 to 18.2 percentage points over prior best results, without any task-specific BEL annotations.
Anthology ID:
2026.findings-emnlp.1109
Volume:
Findings of the Association for Computational Linguistics: EMNLP 2026
Month:
October
Year:
2026
Address:
Budapest, Hungary
Editors:
Hung-Yi Lee, Sunipa Dev, Jessy Li, Desmond Elliott
Venue:
Findings
SIG:
SIGDAT
Publisher:
Association for Computational Linguistics
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Pages:
23462–23488
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URL:
https://aclanthology.org/2026.findings-emnlp.1109/
DOI:
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Cite (ACL):
Yi Wang, Corina Dima, Liangyu Zhong, and Steffen Staab. 2026. BioELX: Context-Aware Cross-lingual Biomedical Entity Linking without Task-Specific Supervision. In Findings of the Association for Computational Linguistics: EMNLP 2026, pages 23462–23488, Budapest, Hungary. Association for Computational Linguistics.
Cite (Informal):
BioELX: Context-Aware Cross-lingual Biomedical Entity Linking without Task-Specific Supervision (Wang et al., Findings 2026)
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PDF:
https://aclanthology.org/2026.findings-emnlp.1109.pdf