LLaVA-RadZ: Can Multimodal Large Language Models Effectively Tackle Zero-shot Radiology Recognition?

Bangyan Li, Wenxuan Huang, Zhenkun Gao, Yeqiang Wang, Yuxiang Shen


Abstract
Recently, Multimodal Large Language Models (MLLMs) have demonstrated strong visual understanding and reasoning abilities across vision-language tasks. However, conventional Visual Question Answering (VQA) pipelines do not fully exploit the visual features and medical knowledge captured by MLLMs, leading to limited performance in zero-shot medical disease recognition. To address this issue, we propose LLaVA-RadZ, a simple yet effective framework for zero-shot radiology recognition. LLaVA-RadZ introduces Decoding-Side Feature Alignment Training (DFAT), which leverages decoder-side representations with modality-specific tokens for image-text alignment, and a Domain Knowledge Anchoring Module (DKAM), which incorporates disease-aware semantic anchors to mitigate the category semantic gap. Extensive experiments show that LLaVA-RadZ substantially improves the zero-shot disease recognition ability of MLLMs and achieves competitive performance compared with well-established CLIP-based radiology recognition methods.
Anthology ID:
2026.findings-emnlp.1204
Volume:
Findings of the Association for Computational Linguistics: EMNLP 2026
Month:
October
Year:
2026
Address:
Budapest, Hungary
Editors:
Hung-Yi Lee, Sunipa Dev, Jessy Li, Desmond Elliott
Venue:
Findings
SIG:
SIGDAT
Publisher:
Association for Computational Linguistics
Note:
Pages:
25435–25454
Language:
URL:
https://aclanthology.org/2026.findings-emnlp.1204/
DOI:
Bibkey:
Cite (ACL):
Bangyan Li, Wenxuan Huang, Zhenkun Gao, Yeqiang Wang, and Yuxiang Shen. 2026. LLaVA-RadZ: Can Multimodal Large Language Models Effectively Tackle Zero-shot Radiology Recognition?. In Findings of the Association for Computational Linguistics: EMNLP 2026, pages 25435–25454, Budapest, Hungary. Association for Computational Linguistics.
Cite (Informal):
LLaVA-RadZ: Can Multimodal Large Language Models Effectively Tackle Zero-shot Radiology Recognition? (Li et al., Findings 2026)
Copy Citation:
PDF:
https://aclanthology.org/2026.findings-emnlp.1204.pdf