Are LLMs Ready to Assist Physicians? PhysAssistBench for Interactive Doctor-Patient-EHR Assistance

Tianming Du, Peijie Yu, Sihan Shang, Danli Shi, My Linh Nguyen, Shengbo Gao, Guangyuan Li, Yinghong Yu, Yan Jiang, Qianlong Zhao, Behzad Bozorgtabar, Shaoxiong Ji, Jiazhen Pan, Daniel Rueckert, Jiancheng Yang


Abstract
The most plausible near-term role of medical LLMs is to assist rather than replace physicians, yet current evaluations often test isolated capabilities: clinical knowledge, EHR system interaction, or patient communication. Physician assistance instead requires coordinating these capabilities within the same interaction, where physicians issue underspecified requests, patients describe symptoms ambiguously, and EHR systems demand precise tool use. We introduce PhysAssistBench, a benchmark for interactive doctor-patient-EHR assistance. Built from real MIMIC-IV cases, PhysAssistBench uses a scalable pipeline to construct agentic patients: interactive, record-grounded agents that turn static EHR records into multi-turn clinical scenarios while preserving clinical factuality. PhysAssistBench provides a curated evaluation set of 1,296 manually reviewed and physician-validated turns. Experiments with leading LLMs show that current models remain unreliable in this setting, struggling to infer physician intent, clarify vague patient descriptions, formulate grounded EHR queries, and integrate evidence across sources. These results expose a key bottleneck for clinical LLMs: reliable assistance requires coordination across knowledge, communication, and systems, not isolated gains in any of them.
Anthology ID:
2026.findings-emnlp.954
Volume:
Findings of the Association for Computational Linguistics: EMNLP 2026
Month:
October
Year:
2026
Address:
Budapest, Hungary
Editors:
Hung-Yi Lee, Sunipa Dev, Jessy Li, Desmond Elliott
Venue:
Findings
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SIGDAT
Publisher:
Association for Computational Linguistics
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Pages:
20108–20142
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URL:
https://aclanthology.org/2026.findings-emnlp.954/
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Cite (ACL):
Tianming Du, Peijie Yu, Sihan Shang, Danli Shi, My Linh Nguyen, Shengbo Gao, Guangyuan Li, Yinghong Yu, Yan Jiang, Qianlong Zhao, Behzad Bozorgtabar, Shaoxiong Ji, Jiazhen Pan, Daniel Rueckert, and Jiancheng Yang. 2026. Are LLMs Ready to Assist Physicians? PhysAssistBench for Interactive Doctor-Patient-EHR Assistance. In Findings of the Association for Computational Linguistics: EMNLP 2026, pages 20108–20142, Budapest, Hungary. Association for Computational Linguistics.
Cite (Informal):
Are LLMs Ready to Assist Physicians? PhysAssistBench for Interactive Doctor-Patient-EHR Assistance (Du et al., Findings 2026)
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https://aclanthology.org/2026.findings-emnlp.954.pdf