Persona-Conditioned Generation of Patient Self-Reports from EHRs

Yuexin Wu, Jianming Wei, Vasile Rus


Abstract
Accurate diagnosis depends not only on clinical expertise but also on how patients describe their symptoms at first contact. Yet large English corpora of patient-authored self-reports are scarce, limiting advances in natural, context-aware narrative modeling. We address this gap by generating first-person self-reports from structured EHR content conditioned on persona attributes that capture social and clinical context. Reports are produced by two generators and scored by two independent graders using a rubric with four dimensions, complemented by a rubric-free preference test. Across 10k stratified cases, we compare two generators under a reliable evaluation protocol and select the higher-scoring one based primarily on Clinical Correctness and Faithfulness, yielding a dataset composed of narratives from the stronger system. Our contributions are threefold: (I) we developed and release a large, persona-conditioned dataset of patient-style self-reports grounded in patient-stated EHR facts, (II) we introduce a transparent evaluation framework that combines rubric-based scoring with rubric-free preference to mitigate grader bias and enable cross-validation, (III) we find that graders exhibit systematic stylistic preferences in rubric-free approach that influence scores independent of clinical content, and (IV) we study large language models for producing first-person self-reports from structured EHRs, highlighting where they succeed, where they fail, and how this affects use in telemedicine and triage.
Anthology ID:
2026.lrec-1.845
Volume:
Proceedings of the Fifteenth Language Resources and Evaluation Conference
Month:
May
Year:
2026
Address:
Palma de Mallorca, Spain
Editors:
Stelios Piperidis, Núria Bel, Henk van den Heuvel, Nancy Ide, Simon Krek, Antonio Toral
Venue:
LREC
SIG:
Publisher:
ELRA Language Resource Association
Note:
Pages:
10792–10801
Language:
External URL:
https://lrec.elra.info/lrec2026-main-845
DOI:
10.63317/34prj6o9qfrk
Bibkey:
Cite (ACL):
Yuexin Wu, Jianming Wei, and Vasile Rus. 2026. Persona-Conditioned Generation of Patient Self-Reports from EHRs. In Proceedings of the Fifteenth Language Resources and Evaluation Conference, pages 10792–10801, Palma de Mallorca, Spain. ELRA Language Resource Association.
Cite (Informal):
Persona-Conditioned Generation of Patient Self-Reports from EHRs (Wu et al., LREC 2026)
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