Negation is an important characteristic of language, and a major component of information extraction from text. This subtask is of considerable importance to the biomedical domain. Over the years, multiple approaches have been explored to address this problem: Rule-based systems, Machine Learning classifiers, Conditional Random Field models, CNNs and more recently BiLSTMs. In this paper, we look at applying Transfer Learning to this problem. First, we extensively review previous literature addressing Negation Detection and Scope Resolution across the 3 datasets that have gained popularity over the years: the BioScope Corpus, the Sherlock dataset, and the SFU Review Corpus. We then explore the decision choices involved with using BERT, a popular transfer learning model, for this task, and report state-of-the-art results for scope resolution across all 3 datasets. Our model, referred to as NegBERT, achieves a token level F1 score on scope resolution of 92.36 on the Sherlock dataset, 95.68 on the BioScope Abstracts subcorpus, 91.24 on the BioScope Full Papers subcorpus, 90.95 on the SFU Review Corpus, outperforming the previous state-of-the-art systems by a significant margin. We also analyze the model’s generalizability to datasets on which it is not trained.

Detecting negation and speculation in language has been a task of considerable interest to the biomedical community, as it is a key component of Information Extraction systems from Biomedical documents. Prior work has individually addressed Negation Detection and Speculation Detection, and both have been addressed in the same way, using 2 stage pipelined approach: Cue Detection followed by Scope Resolution. In this paper, we propose Multitask learning approaches over 2 sets of tasks: Negation Cue Detection & Speculation Cue Detection, and Negation Scope Resolution & Speculation Scope Resolution. We utilise transformer-based architectures like BERT, XLNet and RoBERTa as our core model architecture, and finetune these using the Multitask learning approaches. We show that this Multitask Learning approach outperforms the single task learning approach, and report new state-of-the-art results on Negation and Speculation Scope Resolution on the BioScope Corpus and the SFU Review Corpus.