In high-stakes domains such as healthcare, privacy concerns severely limit the use of real-world training data. Differentially private (DP) synthetic data offers a promising alternative with formal privacy guarantees, but achieving strong utility remains challenging for clinical note generation due to domain specificity and long-form text complexity. We present Term2Note, a method for synthesising full-length clinical notes under strong DP constraints. By structurally separating content and form, Term2Note generates section-wise note content conditioned on medical terms, with terms and notes privatised under separate DP constraints, and applies a DP quality maximiser to improve outputs. Experiments demonstrate that Term2Note produces synthetic notes with statistical properties closely aligned with real clinical notes, and that downstream models trained on these notes achieve performance comparable to those trained on real clinical data. Compared to existing DP text generation baselines, Term2Note substantially improves both fidelity and utility, without relying on label distribution assumptions, highlighting its effectiveness as a practical privacy-preserving alternative to real clinical notes.

Clinical abstractive summarization struggles to balance faithfulness and informativeness, sacrificing key information or introducing confabulations. Techniques like in-context learning and fine-tuning have improved overall summary quality orthogonally, without considering the above issue. Conversely, methods aimed at improving faithfulness and informativeness, such as model reasoning and self improvement, have not been systematically evaluated in the clinical domain. We address this gap by first performing a comprehensive benchmark and study of six advanced abstractive summarization methods across three datasets using five reference-based and reference-free metrics, with the latter specifically assessing faithfulness and informativeness. Based on its findings we then develop uMedSum, a modular hybrid framework introducing novel approaches for sequential confabulation removal and key information addition. Our work outperforms previous GPT-4-based state-of-the-art (SOTA) methods in both quantitative metrics and expert evaluations, achieving an 11.8% average improvement in dedicated faithfulness metrics over the previous SOTA. Doctors prefer uMedSum’s summaries 6 times more than previous SOTA in difficult cases containing confabulations or missing information. These results highlight uMedSum’s effectiveness and generalizability across various datasets and metrics, marking a significant advancement in clinical summarization. uMedSum toolkit is made available on GitHub.