Large language models (LLMs) have shown strong performance on medical question answering benchmarks, yet existing evaluations remain limited in assessing longitudinal clinical reasoning across multiple hospital admissions. We introduce ChronoClinQA, a large-scale benchmark for longitudinal clinical reasoning grounded in multi-admission electronic health records. Built from longitudinal discharge summaries in MIMIC-IV-Note, ChronoClinQA contains 15,067 QA pairs spanning six clinically grounded reasoning dimensions and three complementary question formats: open-ended, adversarial, and unanswerable multiple-choice questions. Each instance requires reasoning over temporally accumulated patient trajectories, with contexts averaging over 16K tokens across up to eight hospital admissions. Experiments on both general-purpose and medical LLMs reveal substantial performance degradation in longitudinal and adversarial settings, highlighting persistent challenges in integrating cross-admission evidence and in temporal clinical reasoning. Our findings position ChronoClinQA as a challenging benchmark for advancing clinically grounded long-context reasoning in medical LLMs.

Graph-based retrieval-augmented generation (GraphRAG) has recently emerged as a powerful paradigm for knowledge-intensive question answering, especially for tasks that require structured evidence organization and multi-hop reasoning. However, existing GraphRAG systems are typically built in a one-size-fits-all manner, relying on a fixed retrieval framework and a single, often large and costly, generator LLM for all queries. This static design limits their ability to adapt to the complexity of varying questions and often incurs unnecessary computational cost. To fill in the gap, we propose GraphRAG-Router, a cost-efficient framework that adopts a hierarchical routing strategy to coordinate heterogeneous GraphRAGs and generator LLMs. Specifically, GraphRAG-Router is first warmed up through supervised fine-tuning and then optimized with a two-stage reinforcement learning procedure, whose second stage introduces a curriculum cost-aware reward to encourage difficulty-aware and economical generator allocation. Extensive experiments on six general-domain and multi-hop QA benchmarks show that GraphRAG-Router consistently outperforms state-of-the-art baselines, reducing the overuse of large LLMs by nearly 30% while maintaining strong generalization capability.

Large Language Models (LLMs) increasingly rely on agentic capabilities—iterative retrieval, tool use, and decision-making—to overcome the limits of static, parametric knowledge. Yet existing agentic frameworks treat external information as unstructured text and fail to leverage the topological dependencies inherent in real-world data. To bridge this gap, we introduce Agentic Graph Learning (AGL), a paradigm that reframes graph learning as an interleaved process of topology-aware navigation and LLM-based inference. Specifically, we propose AgentGL, the first reinforcement learning (RL)–driven framework for AGL. AgentGL equips an LLM agent with graph-native tools for multi-scale exploration, regulates tool usage via search-constrained thinking to balance accuracy and efficiency, and employs a graph-conditioned curriculum RL strategy to stabilize long-horizon policy learning without step-wise supervision. Across diverse Text-Attributed Graph (TAG) benchmarks and multiple LLM backbones, AgentGL substantially outperforms strong GraphLLMs and GraphRAG baselines, achieving absolute improvements of up to 17.5% in node classification and 28.4% in link prediction. These results demonstrate that AGL is a promising frontier for enabling LLMs to autonomously navigate and reason over complex relational environments. The code is publicly available at https://github.com/sunyuanfu/AgentGL.