The 2024 Shared Task on Chemotherapy Treatment Timeline Extraction aims to advance the state of the art of clinical event timeline extraction from the Electronic Health Records (EHRs). Specifically, this edition focuses on chemotherapy event timelines from EHRs of patients with breast, ovarian and skin cancers. These patient-level timelines present a novel challenge which involves tasks such as the extraction of relevant events, time expressions and temporal relations from each document and then summarizing over the documents. De-identified EHRs for 57,530 patients with breast and ovarian cancer spanning 2004-2020, and approximately 15,946 patients with melanoma spanning 2010-2020 were made available to participants after executing a Data Use Agreement. A subset of patients is annotated for gold entities, time expressions, temporal relations and patient-level timelines. The rest is considered unlabeled data. In Subtask1, gold chemotherapy event mentions and time expressions are provided (along with the EHR notes). Participants are asked to build the patient-level timelines using gold annotations as input. Thus, the subtask seeks to explore the topics of temporal relations extraction and timeline creation if event and time expression input is perfect. In Subtask2, which is the realistic real-world setting, only EHR notes are provided. Thus, the subtask aims at developing an end-to-end system for chemotherapy treatment timeline extraction from patient’s EHR notes. There were 18 submissions for Subtask 1 and 9 submissions for Subtask 2. The organizers provided a baseline system. The teams employed a variety of methods including Logistic Regression, TF-IDF, n-grams, transformer models, zero-shot prompting with Large Language Models (LLMs), and instruction tuning. The gap in performance between prompting LLMs and finetuning smaller-sized LMs indicates that for a challenging task such as patient-level chemotherapy timeline extraction, more sophisticated LLMs or prompting techniques are necessary in order to achieve optimal results as finetuing smaller-sized LMs outperforms by a wide margin.

Natural language processing (NLP) research combines the study of universal principles, through basic science, with applied science targeting specific use cases and settings. However, the process of exchange between basic NLP and applications is often assumed to emerge naturally, resulting in many innovations going unapplied and many important questions left unstudied. We describe a new paradigm of Translational NLP, which aims to structure and facilitate the processes by which basic and applied NLP research inform one another. Translational NLP thus presents a third research paradigm, focused on understanding the challenges posed by application needs and how these challenges can drive innovation in basic science and technology design. We show that many significant advances in NLP research have emerged from the intersection of basic principles with application needs, and present a conceptual framework outlining the stakeholders and key questions in translational research. Our framework provides a roadmap for developing Translational NLP as a dedicated research area, and identifies general translational principles to facilitate exchange between basic and applied research.

Embeddings of words and concepts capture syntactic and semantic regularities of language; however, they have seen limited use as tools to study characteristics of different corpora and how they relate to one another. We introduce TextEssence, an interactive system designed to enable comparative analysis of corpora using embeddings. TextEssence includes visual, neighbor-based, and similarity-based modes of embedding analysis in a lightweight, web-based interface. We further propose a new measure of embedding confidence based on nearest neighborhood overlap, to assist in identifying high-quality embeddings for corpus analysis. A case study on COVID-19 scientific literature illustrates the utility of the system. TextEssence can be found at https://textessence.github.io.