Depression is a critical concern in global mental health, prompting extensive research into AI-based detection methods. Among various AI technologies, Large Language Models (LLMs) stand out for their versatility in healthcare applications. However, the application of LLMs in the identification and analysis of depressive states remains relatively unexplored, presenting an intriguing avenue for future research. In this paper, we present an innovative approach to employ an LLM in the realm of depression detection, integrating acoustic speech information into the LLM framework for this specific application. We investigate an efficient method for automatic depression detection by integrating speech signals into LLMs utilizing Acoustic Landmarks. This approach is not only valuable for the detection of depression but also represents a new perspective in enhancing the ability of LLMs to comprehend and process speech signals. By incorporating acoustic landmarks, which are specific to the pronunciation of spoken words, our method adds critical dimensions to text transcripts. This integration also provides insights into the unique speech patterns of individuals, revealing the potential mental states of individuals. By encoding acoustic landmarks information into LLMs, evaluations of the proposed approach on the DAIC-WOZ dataset reveal state-of-the-art results when compared with existing Audio-Text baselines.

Recently, Denoising Diffusion Probabilistic Models (DDPMs) have attained leading performances across a diverse range of generative tasks. However, in the field of speech synthesis, although DDPMs exhibit impressive performance, their prolonged training duration and substantial inference costs hinder practical deployment. Existing approaches primarily focus on enhancing inference speed, while approaches to accelerate training—a key factor in the costs associated with adding or customizing voices—often necessitate complex modifications to the model, compromising their universal applicability. To address the aforementioned challenges, we propose an inquiry: is it possible to enhance the training/inference speed and performance of DDPMs by modifying the speech signal itself? In this paper, we double the training and inference speed of Speech DDPMs by simply redirecting the generative target to the wavelet domain. This method not only achieves comparable or superior performance to the original model in speech synthesis tasks but also demonstrates its versatility. By investigating and utilizing different wavelet bases, our approach proves effective not just in speech synthesis, but also in speech enhancement.