Hengxing Cai
Author directory2026
MppReasoner: Reasoning-Enhanced Large Language Models for Molecular Property Prediction
Jiaxi Zhuang | Yaorui Shi | Jue Hou | Mingwei Ye | Mingjun Xu | Yuming Su | Linfeng Zhang | Ying Qian | Linfeng Zhang | Guolin Ke | Hengxing Cai
Findings of the Association for Computational Linguistics: EMNLP 2026
Jiaxi Zhuang | Yaorui Shi | Jue Hou | Mingwei Ye | Mingjun Xu | Yuming Su | Linfeng Zhang | Ying Qian | Linfeng Zhang | Guolin Ke | Hengxing Cai
Findings of the Association for Computational Linguistics: EMNLP 2026
Molecular property prediction is fundamental to drug discovery and materials science, yet existing models suffer from limited interpretability and poor cross-task generalization. Without explainable chemical rationales, accurate predictions alone are insufficient for guiding costly downstream experiments. We propose MppReasoner, a multimodal large language model that incorporates verifiable chemical reasoning for molecular property prediction. Built on Qwen2.5-VL-7B-Instruct, MppReasoner integrates 2D molecular images with SMILES strings through a two-stage training strategy: supervised fine-tuning (SFT) on 16,000 expert-guided reasoning trajectories, followed by Reinforcement Learning from Principle-Guided Rewards (RLPGR). RLPGR applies rule-based rewards verified by RDKit to evaluate chemical principle usage, structural analysis, and logical consistency, providing objective feedback without human preference labels. Experiments across 8 benchmark datasets show that MppReasoner outperforms the strongest baseline by 2.95% and 5.49% on in-distribution and out-of-distribution tasks, respectively. Beyond predictive accuracy, MppReasoner generates chemically grounded reasoning traces, with expert evaluation confirming high reasoning quality across three assessed dimensions. Code is available at https://github.com/Jesse-zjx/MPPReasoner.
2025
SciAssess: Benchmarking LLM Proficiency in Scientific Literature Analysis
Hengxing Cai | Xiaochen Cai | Junhan Chang | Sihang Li | Lin Yao | Wang Changxin | Zhifeng Gao | Hongshuai Wang | Li Yongge | Mujie Lin | Shuwen Yang | Jiankun Wang | Mingjun Xu | Jin Huang | Xi Fang | Jiaxi Zhuang | Yuqi Yin | Yaqi Li | Changhong Chen | Zheng Cheng | Zifeng Zhao | Linfeng Zhang | Guolin Ke
Findings of the Association for Computational Linguistics: NAACL 2025
Hengxing Cai | Xiaochen Cai | Junhan Chang | Sihang Li | Lin Yao | Wang Changxin | Zhifeng Gao | Hongshuai Wang | Li Yongge | Mujie Lin | Shuwen Yang | Jiankun Wang | Mingjun Xu | Jin Huang | Xi Fang | Jiaxi Zhuang | Yuqi Yin | Yaqi Li | Changhong Chen | Zheng Cheng | Zifeng Zhao | Linfeng Zhang | Guolin Ke
Findings of the Association for Computational Linguistics: NAACL 2025
Recent breakthroughs in Large Language Models (LLMs) have revolutionized scientific literature analysis. However, existing benchmarks fail to adequately evaluate the proficiency of LLMs in this domain, particularly in scenarios requiring higher-level abilities beyond mere memorization and the handling of multimodal data.In response to this gap, we introduce SciAssess, a benchmark specifically designed for the comprehensive evaluation of LLMs in scientific literature analysis. It aims to thoroughly assess the efficacy of LLMs by evaluating their capabilities in Memorization (L1), Comprehension (L2), and Analysis & Reasoning (L3). It encompasses a variety of tasks drawn from diverse scientific fields, including biology, chemistry, material, and medicine.To ensure the reliability of SciAssess, rigorous quality control measures have been implemented, ensuring accuracy, anonymization, and compliance with copyright standards. SciAssess evaluates 11 LLMs, highlighting their strengths and areas for improvement. We hope this evaluation supports the ongoing development of LLM applications in scientific literature analysis.SciAssess and its resources are available at https://github.com/sci-assess/SciAssess.
FlightGPT: Towards Generalizable and Interpretable UAV Vision-and-Language Navigation with Vision-Language Models
Hengxing Cai | Jinhan Dong | Jingjun Tan | Jingcheng Deng | Sihang Li | Zhifeng Gao | Haidong Wang | Zicheng Su | Agachai Sumalee | Renxin Zhong
Proceedings of the 2025 Conference on Empirical Methods in Natural Language Processing
Hengxing Cai | Jinhan Dong | Jingjun Tan | Jingcheng Deng | Sihang Li | Zhifeng Gao | Haidong Wang | Zicheng Su | Agachai Sumalee | Renxin Zhong
Proceedings of the 2025 Conference on Empirical Methods in Natural Language Processing
Unmanned Aerial Vehicle (UAV) Vision-and-Language Navigation (VLN) is vital for applications such as disaster response, logistics delivery, and urban inspection. However, existing methods often struggle with insufficient multimodal fusion, weak generalization, and poor interpretability. To address these challenges, we propose FlightGPT, a novel UAV VLN framework built upon Vision-Language Models (VLMs) with powerful multimodal perception capabilities. We design a two-stage training pipeline: first, Supervised Fine-Tuning (SFT) using high-quality demonstrations to improve initialization and structured reasoning; then, Group Relative Policy Optimization (GRPO) algorithm, guided by a composite reward that considers goal accuracy, reasoning quality, and format compliance, to enhance generalization and adaptability. Furthermore, FlightGPT introduces a Chain-of-Thought (CoT)-based reasoning mechanism to improve decision interpretability. Extensive experiments on the city-scale dataset CityNav demonstrate that FlightGPT achieves state-of-the-art performance across all scenarios, with a 9.22% higher success rate than the strongest baseline in unseen environments. Our implementation is publicly available.
2022
A GlobalPointer based Robust Approach for Information Extraction from Dialog Transcripts
Yanbo J. Wang | Sheng Chen | Hengxing Cai | Wei Wei | Kuo Yan | Zhe Sun | Hui Qin | Yuming Li | Xiaochen Cai
Proceedings of the Towards Semi-Supervised and Reinforced Task-Oriented Dialog Systems (SereTOD)
Yanbo J. Wang | Sheng Chen | Hengxing Cai | Wei Wei | Kuo Yan | Zhe Sun | Hui Qin | Yuming Li | Xiaochen Cai
Proceedings of the Towards Semi-Supervised and Reinforced Task-Oriented Dialog Systems (SereTOD)
With the widespread popularisation of intelligent technology, task-based dialogue systems (TOD) are increasingly being applied to a wide variety of practical scenarios. As the key tasks in dialogue systems, named entity recognition and slot filling play a crucial role in the completeness and accuracy of information extraction. This paper is an evaluation paper for Sere-TOD 2022 Workshop challenge (Track 1 Information extraction from dialog transcripts). We proposed a multi-model fusion approach based on GlobalPointer, combined with some optimisation tricks, finally achieved an entity F1 of 60.73, an entity-slot-value triple F1 of 56, and an average F1 of 58.37, and got the highest score in SereTOD 2022 Workshop challenge
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Co-authors
- Xiaochen Cai 2
- Zhifeng Gao 2
- Guolin Ke 2
- Sihang Li 2
- Mingjun Xu 2
- Linfeng Zhang 2
- Jiaxi Zhuang 2
- Junhan Chang 1
- Wang Changxin 1
- Changhong Chen 1
- Sheng Chen 1
- Zheng Cheng 1
- Jingcheng Deng (邓竞成) 1
- Jinhan Dong 1
- Xi Fang 1
- Jue Hou 1
- Jin Huang 1
- Yaqi Li 1
- Yuming Li 1
- Mujie Lin 1
- Ying Qian 1
- Hui Qin 1
- Yaorui Shi 1
- Yuming Su 1
- Zicheng Su 1
- Agachai Sumalee 1
- Zhe Sun 1
- Jingjun Tan 1
- Haidong Wang 1
- Hongshuai Wang 1
- Jiankun Wang 1
- Yanbo J. Wang 1
- Wei Wei 1
- Kuo Yan 1
- Shuwen Yang 1
- Lin Yao 1
- Mingwei Ye 1
- Yuqi Yin 1
- Li Yongge 1
- Linfeng Zhang 1
- Zifeng Zhao 1
- Renxin Zhong 1