Fine-tuning Large Language Models on a political topic will significantly manipulate their political stance on various issues and unintentionally affect their stance on broad topics. While previous studies have proposed this issue, there is still a lack of understanding regarding the internal representations of these stances and the mechanisms that lead to unintended cross-topic generalization. In this paper, we systematically explore the internal mechanisms underlying this phenomenon from a neuron-level perspective and how to mitigate the cross-topic generalization of political fine-tuning. Firstly, we propose Political Neuron Localization through Activation Contrasting (PNLAC) to identify two distinct types of political neurons: general political neurons, which govern stance across multiple political topics, and topic-specific neurons that affect the model’s political stance on individual topics. We find that these political neuron types exist in the middle and later layers across four models and datasets through activation patching experiments. Leveraging these insights, we introduce InhibitFT, an inhibition-based fine-tuning method that effectively mitigates the cross-topic stance generalization. Experimental results demonstrate the robustness of the identified neuron types across various models and datasets and show that InhibitFT significantly reduces the cross-topic stance generalization by 20% on average while preserving topic-specific performance. Moreover, we demonstrate that selectively inhibiting only 5% of neurons is sufficient to effectively mitigate the cross-topic stance generalization.

Rapid integration of large language models (LLMs) into societal applications has intensified concerns about their alignment with universal ethical principles, as their internal value representations remain opaque despite behavioral alignment advancements. Current approaches struggle to systematically interpret how values are encoded in neural architectures, limited by datasets that prioritize superficial judgments over mechanistic analysis. We introduce ValueLocate, a mechanistic interpretability framework grounded in the Schwartz Values Survey, to address this gap. Our method first constructs ValueInsight, a dataset that operationalizes four dimensions of universal value through behavioral contexts in the real world. Leveraging this dataset, we develop a neuron identification method that calculates activation differences between opposing value aspects, enabling precise localization of value-critical neurons without relying on computationally intensive attribution methods. Our proposed validation method demonstrates that targeted manipulation of these neurons effectively alters model value orientations, establishing causal relationships between neurons and value representations. This work advances the foundation for value alignment by bridging psychological value frameworks with neuron analysis in LLMs.