The rapid evolution of reasoning-intensive Large Language Models renders traditional metrics insufficient by masking fine-grained failures and implicit pathologies. Existing weakness discovery methods typically rely on rigid pipelines, yielding superficial insights that lack the diagnostic depth required for effective model improvement. To address this, we introduce Agent4Weakness, a multi-agent framework designed to replicate the rigorous workflow of human expert analysts. By integrating a Domain-Aware Memory for contextual reasoning with diagnostic evaluation skills and a Tool Abstraction mechanism for decouple data analysis, Agent4Weakness transforms raw evaluation traces into grounded, actionable reports. We validate our framework through an extensive study involving 104 models across 27 benchmarks. Experimental results demonstrate that Agent4Weakness produces diagnostic reports significantly superior to competitive baselines. Crucially, leveraging these insights for prompt guidance yields an average 3.7 point performance boost and establishes a closed-loop optimization framework.

Large Language Models (LLMs) perform well on standard reasoning and question-answering benchmarks, yet such evaluations often fail to capture their ability to handle long-tail, expertise-intensive knowledge in real-world professional scenarios. We introduce LPFQA, a long-tail knowledge benchmark derived from authentic professional forum discussions, covering 7 academic and industrial domains with 430 curated tasks grounded in practical expertise. LPFQA evaluates specialized reasoning, domain-specific terminology understanding, and contextual interpretation, and adopts a hierarchical difficulty structure to ensure semantic clarity and uniquely identifiable answers. Experiments on over multiple mainstream LLMs reveal substantial performance gaps, particularly on tasks requiring deep domain reasoning, exposing limitations overlooked by existing benchmarks. Overall, LPFQA provides an authentic and discriminative evaluation framework that complements prior benchmarks and informs future LLM development. Our data is available at https://huggingface.co/datasets/m-a-p/LPFQA.