We present the joint contribution of IST and Unbabel to the WMT 2020 Shared Task on Quality Estimation. Our team participated on all tracks (Direct Assessment, Post-Editing Effort, Document-Level), encompassing a total of 14 submissions. Our submitted systems were developed by extending the OpenKiwi framework to a transformer-based predictor-estimator architecture, and to cope with glass-box, uncertainty-based features coming from neural machine translation systems.