Large language model (LLM) systems increasingly power everyday AI applications such as chatbots, computer-use assistants, and autonomous robots, where performance often depends on manually well-crafted prompts. LLM-based prompt optimizers reduce that effort by iteratively refining prompts from scored feedback, yet the security of this optimization stage remains underexamined. We present the first systematic analysis of poisoning risks in LLM-based prompt optimization. Using HarmBench, we find systems are substantially more vulnerable to manipulated feedback than to query poisoning alone: feedback-based attacks raise attack success rate (ASR) by up to ΔASR = 0.48. We introduce a simple fake reward attack that requires no access to the reward model and significantly increases vulnerability. We also propose a lightweight highlighting defense that reduces the fake reward ΔASR from 0.23 to 0.07 without degrading utility. These results establish prompt optimization pipelines as a first-class attack surface and motivate stronger safeguards for feedback channels and optimization frameworks.

The emerging capabilities of large language models (LLMs) have sparked concerns about their immediate potential for harmful misuse. The core approach to mitigate these concerns is the detection of harmful queries to the model. Current detection approaches are fallible, and are particularly susceptible to attacks that exploit mismatched generalization of model capabilities (e.g., prompts in low-resource languages or prompts provided in non-text modalities such as image and audio). To tackle this challenge, we propose OMNIGUARD, an approach for detecting harmful prompts across languages and modalities. Our approach (i) identifies internal representations of an LLM/MLLM that are aligned across languages or modalities and then (ii) uses them to build a language-agnostic or modality-agnostic classifier for detecting harmful prompts. OMNIGUARD improves harmful prompt classification accuracy by 11.57% over the strongest baseline in a multilingual setting, by 20.44% for image-based prompts, and sets a new SOTA for audio-based prompts. By repurposing embeddings computed during generation, OMNIGUARD is also very efficient (≈ 120× faster than the next fastest baseline). Code and data are available at https://github.com/vsahil/OmniGuard