A shift in data distribution can have a significant impact on performance of a text classification model. Recent methods addressing unsupervised domain adaptation for textual tasks typically extracted domain-invariant representations through balancing between multiple objectives to align feature spaces between source and target domains. While effective, these methods induce various new domain-sensitive hyperparameters, thus are impractical as large-scale language models are drastically growing bigger to achieve optimal performance. To this end, we propose to leverage meta-learning framework to train a neural network-based self-paced learning procedure in an end-to-end manner. Our method, called Meta Self-Paced Domain Adaption (MSP-DA), follows a novel but intuitive domain-shift variation of cluster assumption to derive the meta train-test dataset split based on the self-pacing difficulties of source domain’s examples. As a result, MSP-DA effectively leverages self-training and self-tuning domain-specific hyperparameters simultaneously throughout the learning process. Extensive experiments demonstrate our framework substantially improves performance on target domains, surpassing state-of-the-art approaches. Detailed analyses validate our method and provide insight into how each domain affects the learned hyperparameters.