Although current state-of-the-art Transformer-based solutions succeeded in a wide range for single-document NLP tasks, they still struggle to address multi-input tasks such as multi-document summarization. Many solutions truncate the inputs, thus ignoring potential summary-relevant contents, which is unacceptable in the medical domain where each information can be vital. Others leverage linear model approximations to apply multi-input concatenation, worsening the results because all information is considered, even if it is conflicting or noisy with respect to a shared background. Despite the importance and social impact of medicine, there are no ad-hoc solutions for multi-document summarization. For this reason, we propose a novel discriminative marginalized probabilistic method (DAMEN) trained to discriminate critical information from a cluster of topic-related medical documents and generate a multi-document summary via token probability marginalization. Results prove we outperform the previous state-of-the-art on a biomedical dataset for multi-document summarization of systematic literature reviews. Moreover, we perform extensive ablation studies to motivate the design choices and prove the importance of each module of our method.

The latest batch of research has equipped language models with the ability to attend over relevant and factual information from non-parametric external sources, drawing a complementary path to architectural scaling. Besides mastering language, exploiting and contextualizing the latent world knowledge is crucial in complex domains like biomedicine. However, most works in the field rely on general-purpose models supported by databases like Wikipedia and Books. We introduce BioReader, the first retrieval-enhanced text-to-text model for biomedical natural language processing. Our domain-specific T5-based solution augments the input prompt by fetching and assembling relevant scientific literature chunks from a neural database with ≈60 million tokens centered on PubMed. We fine-tune and evaluate BioReader on a broad array of downstream tasks, significantly outperforming several state-of-the-art methods despite using up to 3x fewer parameters. In tandem with extensive ablation studies, we show that domain knowledge can be easily altered or supplemented to make the model generate correct predictions bypassing the retraining step and thus addressing the literature overload issue.