Biomedical Information Extraction from scientific literature presents two unique and non-trivial challenges. First, compared with general natural language texts, sentences from scientific papers usually possess wider contexts between knowledge elements. Moreover, comprehending the fine-grained scientific entities and events urgently requires domain-specific background knowledge. In this paper, we propose a novel biomedical Information Extraction (IE) model to tackle these two challenges and extract scientific entities and events from English research papers. We perform Abstract Meaning Representation (AMR) to compress the wide context to uncover a clear semantic structure for each complex sentence. Besides, we construct the sentence-level knowledge graph from an external knowledge base and use it to enrich the AMR graph to improve the model’s understanding of complex scientific concepts. We use an edge-conditioned graph attention network to encode the knowledge-enriched AMR graph for biomedical IE tasks. Experiments on the GENIA 2011 dataset show that the AMR and external knowledge have contributed 1.8% and 3.0% absolute F-score gains respectively. In order to evaluate the impact of our approach on real-world problems that involve topic-specific fine-grained knowledge elements, we have also created a new ontology and annotated corpus for entity and event extraction for the COVID-19 scientific literature, which can serve as a new benchmark for the biomedical IE community.

The quadratic computational and memory complexities of large Transformers have limited their scalability for long document summarization. In this paper, we propose Hepos, a novel efficient encoder-decoder attention with head-wise positional strides to effectively pinpoint salient information from the source. We further conduct a systematic study of existing efficient self-attentions. Combined with Hepos, we are able to process ten times more tokens than existing models that use full attentions. For evaluation, we present a new dataset, GovReport, with significantly longer documents and summaries. Results show that our models produce significantly higher ROUGE scores than competitive comparisons, including new state-of-the-art results on PubMed. Human evaluation also shows that our models generate more informative summaries with fewer unfaithful errors.

To combat COVID-19, both clinicians and scientists need to digest the vast amount of relevant biomedical knowledge in literature to understand the disease mechanism and the related biological functions. We have developed a novel and comprehensive knowledge discovery framework, COVID-KG to extract fine-grained multimedia knowledge elements (entities, relations and events) from scientific literature. We then exploit the constructed multimedia knowledge graphs (KGs) for question answering and report generation, using drug repurposing as a case study. Our framework also provides detailed contextual sentences, subfigures, and knowledge subgraphs as evidence. All of the data, KGs, reports.