The success of large language models (LLMs) facilitate many parties to fine-tune LLMs on their own private data. However, this practice raises privacy concerns due to the memorization of LLMs. Existing solutions, such as utilizing synthetic data for substitution, struggle to simultaneously improve performance and preserve privacy.They either rely on a local model for generation, resulting in a performance decline, or take advantage of APIs, directly exposing the data to API servers. To address this issue, we propose KnowledgeSG, a novel client-server framework which enhances synthetic data quality and improves model performance while ensuring privacy. We achieve this by learning local knowledge from the private data with differential privacy (DP) and distilling professional knowledge from the server. Additionally, inspired by federated learning, we transmit models rather than data between the client and server to prevent privacy leakage.Extensive experiments in medical and financial domains demonstrate the effectiveness of *KnowledgeSG*. Our code is now publicly available at https://github.com/wwh0411/KnowledgeSG.

Large language models (LLMs) possess immense capabilities but are susceptible to malicious exploitation. To mitigate the risk, safety alignment is employed to align LLMs with ethical standards. However, safety-aligned LLMs may remain vulnerable to carefully crafted jailbreak attacks, but these attacks often face high rejection rates and limited harmfulness. In this paper, we expose the vulnerabilities of safety alignment in open-access LLMs, which can significantly enhance the success rate and harmfulness of jailbreak attacks. Through reverse alignment, achieved by accessing model parameters, we show the feasibility of efficiently fine-tuning LLMs to undermine their inherent safeguards. We investigate two types of reverse alignment techniques: reverse supervised fine-tuning (RSFT) and reverse preference optimization (RPO). RSFT operates by supervising the fine-tuning of LLMs to reverse their inherent values. We also explore how to prepare data needed for RSFT. RPO optimizes LLMs to enhance their preference for harmful content, reversing the models’ safety alignment. Our extensive experiments reveal that open-access high-performance LLMs can be adeptly reverse-aligned to output harmful content, even in the absence of manually curated malicious datasets. Our research acts as a whistleblower for the community, emphasizing the need to pay more attention to safety of open-accessing LLMs. It also underscores the limitations of current safety alignment approaches and calls for research on robust safety alignment methods to counteract malicious fine-tuning attacks.