Several recent works seek to develop foundation models specifically for medical applications, adapting general-purpose large language models (LLMs) and vision-language models (VLMs) via continued pretraining on publicly available biomedical corpora. These works typically claim that such domain-adaptive pretraining (DAPT) improves performance on downstream medical tasks, such as answering medical licensing exam questions. In this paper, we compare seven public “medical” LLMs and two VLMs against their corresponding base models, arriving at a different conclusion: all medical VLMs and nearly all medical LLMs fail to consistently improve over their base models in the zero-/few-shot prompting regime for medical question-answering (QA) tasks. For instance, across the tasks and model pairs we consider in the 3-shot setting, medical LLMs only outperform their base models in 12.1% of cases, reach a (statistical) tie in 49.8% of cases, and are significantly worse than their base models in the remaining 38.2% of cases. Our conclusions are based on (i) comparing each medical model head-to-head, directly against the corresponding base model; (ii) optimizing the prompts for each model separately; and (iii) accounting for statistical uncertainty in comparisons. While these basic practices are not consistently adopted in the literature, our ablations show that they substantially impact conclusions. Our findings suggest that state-of-the-art general-domain models may already exhibit strong medical knowledge and reasoning capabilities, and offer recommendations to strengthen the conclusions of future studies.

For most natural language processing tasks, the dominant practice is to finetune large pretrained transformer models (e.g., BERT) using smaller downstream datasets. Despite the success of this approach, it remains unclear to what extent these gainsare attributable to the massive background corpora employed for pretraining versus to the pretraining objectives themselves. This paper introduces a large-scale study of self-pretraining, where the same (downstream) training data is used for both pretraining and finetuning.In experiments addressing both ELECTRA and RoBERTa models and 10 distinct downstream classification datasets, we observe that self-pretraining rivals standard pretraining on the BookWiki corpus (despite using around 10x–500x less data), outperforming the latter on 7 and 5 datasets, respectively. Surprisingly, these task-specific pretrained models often perform well on other tasks,including the GLUE benchmark. Besides classification tasks, self-pretraining also provides benefits on structured output prediction tasks such as span based question answering and commonsense inference, often providing more than 50% of the performance boosts provided by pretraining on the BookWiki corpus. Our results hint that in many scenarios, performance gains attributable to pretraining are driven primarily by the pretraining objective itself and are not always attributable to the use of external pretraining data in massive amounts. These findings are especially relevant in light of concerns about intellectual property and offensive content in web-scale pretraining data.

This work focuses on building language models (LMs) for code-switched text. We propose two techniques that significantly improve these LMs: 1) A novel recurrent neural network unit with dual components that focus on each language in the code-switched text separately 2) Pretraining the LM using synthetic text from a generative model estimated using the training data. We demonstrate the effectiveness of our proposed techniques by reporting perplexities on a Mandarin-English task and derive significant reductions in perplexity.