Text simplification aims to make technical texts more accessible to laypeople but often results in deletion of information and vagueness. This work proposes InfoLossQA, a framework to characterize and recover simplification-induced information loss in form of question-and-answer (QA) pairs. Building on the theory of Questions Under Discussion, the QA pairs are designed to help readers deepen their knowledge of a text. First, we collect a dataset of 1,000 linguist-curated QA pairs derived from 104 LLM simplifications of English medical study abstracts. Our analyses of this data reveal that information loss occurs frequently, and that the QA pairs give a high-level overview of what information was lost. Second, we devise two methods for this task: end-to-end prompting of open-source and commercial language models, and a natural language inference pipeline. With a novel evaluation framework considering the correctness of QA pairs and their linguistic suitability, our expert evaluation reveals that models struggle to reliably identify information loss and applying similar standards as humans at what constitutes information loss.

Plain language summarization with LLMs can be useful for improving textual accessibility of technical content. But how factual are these summaries in a high-stakes domain like medicine? This paper presents FactPICO, a factuality benchmark for plain language summarization of medical texts describing randomized controlled trials (RCTs), which are the basis of evidence-based medicine and can directly inform patient treatment. FactPICO consists of 345 plain language summaries of RCT abstracts generated from three LLMs (i.e., GPT-4, Llama-2, and Alpaca), with fine-grained evaluation and natural language rationales from experts. We assess the factuality of critical elements of RCTs in those summaries: Populations, Interventions, Comparators, Outcomes (PICO), as well as the reported findings concerning these. We also evaluate the correctness of the extra information (e.g., explanations) added by LLMs. Using FactPICO, we benchmark a range of existing factuality metrics, including the newly devised ones based on LLMs. We find that plain language summarization of medical evidence is still challenging, especially when balancing between simplicity and factuality, and that existing metrics correlate poorly with expert judgments on the instance level.

Automated text simplification aims to produce simple versions of complex texts. This task is especially useful in the medical domain, where the latest medical findings are typically communicated via complex and technical articles. This creates barriers for laypeople seeking access to up-to-date medical findings, consequently impeding progress on health literacy. Most existing work on medical text simplification has focused on monolingual settings, with the result that such evidence would be available only in just one language (most often, English). This work addresses this limitation via multilingual simplification, i.e., directly simplifying complex texts into simplified texts in multiple languages. We introduce MultiCochrane, the first sentence-aligned multilingual text simplification dataset for the medical domain in four languages: English, Spanish, French, and Farsi. We evaluate fine-tuned and zero-shot models across these languages with extensive human assessments and analyses. Although models can generate viable simplified texts, we identify several outstanding challenges that this dataset might be used to address.

Large language models, particularly GPT-3, are able to produce high quality summaries ofgeneral domain news articles in few- and zero-shot settings. However, it is unclear if such models are similarly capable in more specialized domains such as biomedicine. In this paper we enlist domain experts (individuals with medical training) to evaluate summaries of biomedical articles generated by GPT-3, given no supervision. We consider bothsingle- and multi-document settings. In the former, GPT-3 is tasked with generating regular and plain-language summaries of articles describing randomized controlled trials; in thelatter, we assess the degree to which GPT-3 is able to synthesize evidence reported acrossa collection of articles. We design an annotation scheme for evaluating model outputs, withan emphasis on assessing the factual accuracy of generated summaries. We find that whileGPT-3 is able to summarize and simplify single biomedical articles faithfully, it strugglesto provide accurate aggregations of findings over multiple documents. We release all data,code, and annotations used in this work.