Large Language Models (LLMs) have shown strong potential in medical question answering, but their reliance on static parametric knowledge limits their ability to handle rapidly evolving clinical evidence. The retrieval system mitigates this issue by incorporating external medical knowledge, but flat retrieval can return lexically relevant but clinically misaligned evidence. We propose Med-Chain, a training-free medical evidence retrieval framework that reformulates retrieval as inspectable and repairable clinical evidence paths. Med-Chain first routes each question through a clinical topic tree to progressively narrow retrieval from broad domains to specific guideline sections. It then verifies whether the retrieved path matches the clinical intent and performs level-aware refinement to repair mismatches. Experiments on seven medical QA benchmarks show that Med-Chain consistently improves backbone LLMs and outperforms existing medical Retrieval-augmented generation baselines, highlighting the value of clinically structured and repairable evidence retrieval.

Practical deployment of medical vision-language models requires a single model that interprets heterogeneous clinical visual inputs: 2D images, 3D volumes, and medical videos. Yet how to train such unified models remains underexplored, as these modalities differ in spatial-temporal structure, token length, and data availability. We present OmniV-Med, a scalable training recipe built on four empirical findings. First, broad modality coverage requires balancing modality diversity with task-level supervision, motivating OmniV-Med-Instruct, a 252K corpus spanning 14 medical modalities and 11 clinical tasks. Second, we identify a modality-ordering effect: introducing 3D and video too early destabilizes optimization and weakens 2D grounding, motivating a progressive curriculum that first builds 2D alignment before extending to spatial-temporal inputs. Third, we observe an emergent spatiotemporal transfer effect: once strong 2D patch representations are in place, lightweight rotary position adaptation extrapolates them to 3D slices and video frames, letting a single 2D ViT replace modality-specific encoder stacks. Fourth, the imbalance in sequence length across modalities and the redundancy of long volumes and videos hinder scaling; our Redundancy-Guided Token Pruning (RGTP) exploits inter-slice and inter-frame redundancy to cut visual tokens by 60% while preserving performance. Across nine 2D, 3D, and video medical benchmarks, OmniV-Med achieves robust performance. Extensive component-wise ablations systematically refine the design space, yielding a simple yet efficient and scalable recipe for training high-performance unified Med-VLMs. Code is released at https://github.com/ZJUI-AI4H/Hulu-Med.

While reinforcement learning from verifiable rewards (RLVR) has been proven highly effective for enhancing reasoning, its application to medical visual question answering (Med-VQA) is hampered by models producing reasoning inconsistent with either the visual evidence or the final answer. Our analysis reveals a critical flaw in RLVR training: it paradoxically encourages models to disregard visual evidence and generate answers that contradict their own reasoning. This degradation is most pronounced in specialized medical modalities (e.g., Fundus, Ultrasound) where base VLMs lack robust understanding, a failure we attribute to a flawed reward mechanism exacerbated by the scarcity of diverse training data. To tackle this, we introduce Med-Zero-17K, a large-scale dataset spanning over 30 modalities and 24 clinically relevant tasks, and the Multi-Consistency Reward (MCR) framework, which explicitly rewards both perceptual grounding and logical coherence. Extensive experiments validate our approach: integrating MCR into the RLVR framework delivers robust performance gains. This success stems from our crucial finding that rewarding internal consistency is significantly more effective than attempting to judge reasoning correctness. Furthermore, MCR proves highly versatile, exhibiting strong generalization across diverse VLM backbones, compatibility with RL algorithms like GRPO and DPO, and extending its effectiveness to 3D VQA tasks and R1-style training paradigms. Code and dataset will be released.

Text-Attributed Graphs (TAGs), which integrate text and graph structures, have recently gained traction, especially in web applications. However, as a graph structure, TAG representation learning (TAGRL) naturally inherits issues from Graph Neural Networks (GNNs), such as fairness. Moreover, previous TAGRL research has mainly focused on using LM-as-encoder to boost downstream task performance, with little consideration given to whether this process may raise additional concerns related to fairness and other safety-related issues. As the first work to explore fairness in TAGRL, this paper proposes the concept of evolving LM-as-encoder to LM-as-fair-encoder, developing a two-stage fairness-aware alignment process called FairTAG based on the observed issues. Specifically, we first mitigate the tendency of LMs to overfit to homophily during downstream tasks fine-tuning, followed by subgraph-level connection behavior preference optimization for selected anchor nodes. We provide theoretical support and demonstrate the feasibility of LM-as-fair-encoder through extensive experiments and ablation studies. We also show that FairTAG can be seamlessly integrated with fairness-enhancing strategies on the GNNs decoder side, thus innovatively constructing a plug-and-play learning framework.

Multimodal large language models (MLLMs) still struggle with complex reasoning tasks in Visual Question Answering (VQA). While current methods have advanced by incorporating visual prompts, our study uncovers critical limitations: these approaches indiscriminately annotate all detected objects for every visual question, generating excessive visual markers that degrade task performance. This issue stems primarily from a lack of focus on key visual elements, raising two important questions: Are all objects equally important, and do all questions require visual prompts? Motivated by Dual Process Theory, which distinguishes between instinctive and deliberate cognitive modes in human reasoning, we propose FOCUS, a plug-and-play approach that dynamically adapts to the complexity of questions, combining fast intuitive judgments with deliberate analytical reasoning to enhance the vision-language reasoning capability of the MLLM. For straightforward questions, FOCUS supports efficient zero-shot reasoning. For more complex tasks, it employs the conceptualizing before observation strategy to highlight critical elements. Extensive experiments on four benchmarks—ScienceQA, TextQA, VizWiz, and MME—demonstrate that FOCUS consistently improves the performance of both open-source and black-box MLLMs, achieving significant gains across all datasets. Ablation studies further validate the importance of combining diverse cognitive strategies with refined visual information for superior performance. Code will be released.

Medical Vision-Language Models (Med-VLMs) have achieved success across various tasks, yet most existing methods overlook the modality misalignment issue that can lead to untrustworthy responses in clinical settings. In this paper, we propose Hierarchical Self-Contrastive Rewarding (HSCR), a novel approach that addresses two critical challenges in Med-VLM alignment: 1) Cost-effective generation of high-quality preference data; 2) Capturing nuanced and context-aware preferences for improved alignment. HSCR first leverages the inherent capability of Med-VLMs to generate dispreferred responses with higher sampling probability. By analyzing output logit shifts after visual token dropout, we identify modality-coupled tokens that induce misalignment and derive an implicit alignment reward function. This function guides token replacement with hallucinated ones during decoding, producing high-quality dispreferred data. Furthermore, HSCR introduces a multi-level preference optimization strategy, which extends beyond traditional adjacent-level optimization by incorporating nuanced implicit preferences, leveraging relative quality in dispreferred data to capture subtle alignment cues for more precise and context-aware optimization. Extensive experiments across multiple medical tasks, including Med-VQA, medical image captioning and instruction following, demonstrate that HSCR not only enhances zero-shot performance but also significantly improves modality alignment and trustworthiness with just 2,000 training entries. Code is released on https://github.com/jiangsongtao/HSCR.

Recent advancements in general-purpose or domain-specific multimodal large language models (LLMs) have witnessed remarkable progress for medical decision-making. However, they are designated for specific classification or generative tasks, and require model training or finetuning on large-scale datasets with sizeable parameters and tremendous computing, hindering their clinical utility across diverse resource-constrained scenarios in practice. In this paper, we propose a novel and lightweight framework Med-MoE (Mixture-of-Experts) that tackles both discriminative and generative multimodal medical tasks. The learning of Med-MoE consists of three steps: multimodal medical alignment, Instruction tuning and routing, and domain-specific MoE tuning. After aligning multimodal medical images with LLM tokens, we then enable the model for different multimodal medical tasks with instruction tuning, together with a trainable router tailored for expert selection across input modalities. Finally, the model is tuned by integrating the router with multiple domain-specific experts, which are selectively activated and further empowered by meta experts. Comprehensive experiments on both open- and close-end medical question answering (Med-VQA) and image classification tasks across datasets such as VQA-RAD, SLAKE and Path-VQA demonstrate that our model can achieve performance superior to or on par with state-of-the-art baselines, while only requiring approximately 30%-50% of activated model parameters. Extensive analysis and ablations corroborate the effectiveness and practical utility of our method.