Personalized lifestyle health analysis requires long-horizon, multi-dimensional reasoning over heterogeneous lifestyle signals, and recent advances in mobile sensing and large language models (LLMs) make such support increasingly feasible. However, the capabilities of current LLMs in this setting remain insufficiently understood due to the lack of systematic benchmarks. In this paper, we introduce LifeAgentBench, a large-scale QA benchmark for long-horizon, cross-dimensional, and multi-user lifestyle health reasoning, containing 22,573 questions spanning from basic retrieval to complex reasoning. We release an extensible benchmark construction pipeline and a standardized evaluation protocol, deriving verifiable answers through executable queries and programs to support reliable assessment. We then systematically evaluate 13 representative LLMs on LifeAgentBench and identify key bottlenecks in long-horizon aggregation and cross-dimensional reasoning. Motivated by these findings, we propose LifeAgent, a tool-augmented reasoning baseline that decomposes complex queries, performs multi-step evidence retrieval, and invokes tools for deterministic aggregation. LifeAgent substantially enhances LLMs’ capabilities on challenging reasoning tasks, achieving clear improvements over widely used baselines and showing potential for health reasoning in everyday scenarios. The benchmark is publicly available.

Specializing large language models (LLMs) for local deployment in domain-specific use cases is necessary for strong performance while meeting latency and privacy constraints. However, conventional task-specific adaptation approaches do not show simultaneous memory saving and inference speedup at deployment time. Practical compression techniques like quantization and pruning require dedicated hardware or kernel support to achieve measured inference speedup. We develop TrimLLM based on the layer-wise specialization phenomenon we empirically observed and verified on contemporary LLMs. TrimLLM reduces the depth of LLMs via progressive layer dropping. We show it retains LLMs’ capacity in specific domains and achieves inference speedup irrespective of hardware and deep learning frameworks. We evaluated TrimLLM on LLMs of various sizes for inference; models adapted on medical, legal, and financial datasets all demonstrate 2.1 - 5.7× inference speedup on consumer GPUs and up to 3.1× speedup on A100 when compared to state-of-the-art model compression algorithms, with no loss in accuracy at 50∼ 60% model compression ratio.