Foundation models have demonstrated remarkable capabilities in handling diverse modalities and tasks, outperforming conventional artificial intelligence (AI) approaches that are highly task-specific and modality-reliant. In the medical domain, however, the development of comprehensive foundation models is constrained by limited access to diverse modalities and stringent privacy regulations. To address these constraints, this study introduces a novel knowledge injection approach, FedKIM, designed to scale the medical foundation model within a federated learning framework. FedKIM leverages lightweight local models to extract healthcare knowledge from private data and integrates this knowledge into a centralized foundation model using a designed adaptive Multitask Multimodal Mixture Of Experts (M³OE) module. This method not only preserves privacy but also enhances the model’s ability to handle complex medical tasks involving multiple modalities. Our extensive experiments across twelve tasks in seven modalities demonstrate the effectiveness of FedKIM in various settings, highlighting its potential to scale medical foundation models without direct access to sensitive data. Source codes are available at https://github.com/XiaochenWang-PSU/FedKIM.

As a fundamental task in natural language processing, named entity recognition (NER) aims to locate and classify named entities in unstructured text. However, named entities are always the minority among all tokens in the text. This data imbalance problem presents a challenge to machine learning models as their learning objective is usually dominated by the majority of non-entity tokens. To alleviate data imbalance, we propose a set of sentence-level resampling methods where the importance of each training sentence is computed based on its tokens and entities. We study the generalizability of these resampling methods on a wide variety of NER models (CRF, Bi-LSTM, and BERT) across corpora from diverse domains (general, social, and medical texts). Extensive experiments show that the proposed methods improve span-level macro F1-scores of the evaluated NER models on multiple corpora, frequently outperforming sub-sentence-level resampling, data augmentation, and special loss functions such as focal and Dice loss.