Large language models (LLMs) finetuned for specialized domains represent crucial high-impact applications. Inference-time alignment improves safety degraded from specialization finetuning without requiring substantial computational resources, complementing finetuning-based methods with an easy-to-use, plug-and-play solution. However, existing inference-time methods fail to reliably improve safety without disrupting domain capability. We identify the root cause as complementary expertise orthogonality: specialized base models and general-domain guidance models have orthogonal competencies, making the guidance signal unreliable for specialized generation. This primarily manifests as stop token interference, where the guidance model’s tendency toward continuation overrides the base model’s decision to stop, burying correct answers under guidance-induced continuation. To address this problem, we propose CREST, an inference-time alignment method that steers base model hidden representations using safety directions extracted from a guidance model of any family, avoiding token-level structural limitations entirely. CREST improves safety where specialization has weakened it while preserving both domain-specific capability and the safety of already well-aligned models, outperforming baselines by up to 22.2% on safety benchmarks. Our code is available at: https://github.com/DecayingSeart/CREST.

The wide deployment of LLMs has made model alignment necessary to make newly trained models safely and effectively respond to user instructions. Among different methods, inference-time alignment is often cheaper as it intervenes (i.e., offers guidances) only during output generation. Existing proposals apply guidances extracted from certain aligned models without properly assessing their reliability. Nonetheless, our systematic evaluation reveals that guidance effectiveness varies drastically across models; since ineffective guidances lead to further confusion and thus further interventions, the resulting excessive interventions typically indicate poor performance. To make interventions more effective and thus more efficient, we introduce BlendIn, an inference-time alignment framework that shifts from binary decisions to creating hybrid distributions integrating both models’ knowledge. BlendIn stabilizes inference-time alignment by performing quality-aware alignment and proportionally weighting each model’s contribution based on reliability. Compared with existing works, it preserves beneficial guidance while downweighting unreliable suggestions. BlendIn provides both diagnostic signals and mitigation strategies for misaligned guidance, achieving consistent and up to 50% performance improvement on challenging model pairs. Our code is available at: https://github.com/DecayingSeart/BlendIn.