The rapid growth in published clinical trials makes it difficult to maintain up-to-date systematic reviews, which require finding all relevant trials. This leads to policy and practice decisions based on out-of-date, incomplete, and biased subsets of available clinical evidence. Extracting and then normalising Population, Intervention, Comparator, and Outcome (PICO) information from clinical trial articles may be an effective way to automatically assign trials to systematic reviews and avoid searching and screening—the two most time-consuming systematic review processes. We propose and test a novel approach to PICO span detection. The major difference between our proposed method and previous approaches comes from detecting spans without needing annotated span data and using only crowdsourced sentence-level annotations. Experiments on two datasets show that PICO span detection results achieve much higher results for recall when compared to fully supervised methods with PICO sentence detection at least as good as human annotations. By removing the reliance on expert annotations for span detection, this work could be used in a human-machine pipeline for turning low-quality, crowdsourced, and sentence-level PICO annotations into structured information that can be used to quickly assign trials to relevant systematic reviews.

There are many different ways in which external information might be used in a NLP task. This paper investigates how external syntactic information can be used most effectively in the Semantic Role Labeling (SRL) task. We evaluate three different ways of encoding syntactic parses and three different ways of injecting them into a state-of-the-art neural ELMo-based SRL sequence labelling model. We show that using a constituency representation as input features improves performance the most, achieving a new state-of-the-art for non-ensemble SRL models on the in-domain CoNLL’05 and CoNLL’12 benchmarks.