Visually Rich Document Understanding (VRDU) has become a pivotal area of research, driven by the need to automatically interpret documents that contain intricate visual, textual, and structural elements. Recently, Multimodal Large Language Models (MLLMs) have demonstrated significant promise in this domain, including both OCR-based and OCR-free approaches for information extraction from document images. This survey reviews recent advances in MLLM-based VRDU, highlighting emerging trends and promising research directions with a focus on two key aspects: (1) techniques for representing and integrating textual, visual, and layout features; (2) training paradigms, including pretraining, instruction tuning, and training strategies. Moreover, we address challenges such as data scarcity, handling multi-page and multilingual documents, and integrating emerging trends such as Retrieval-Augmented Generation and agentic frameworks. Our analysis offers a roadmap for advancing MLLM-based VRDU toward more scalable, reliable, and adaptable systems.

Documents spanning tens to hundreds of pages are pervasive in real-world workflows, from scientific papers to financial reports and technical manuals. In this setting, answer-relevant evidence is sparse and distributed across pages, and the document itself often exceeds a backbone MLLM’s context window, making MP-VRDU a distinct problem from single-page VRDU. We survey MP-VRDU through the lens of evidence management, the organising principle that distinguishes multi-page from the single-page setting: the problem of deciding how document-scale evidence is selected and reasoned over when it cannot all be held at once. We introduce a taxonomy spanning four architectural families, multimodal representation, inference-time adaptation, and training strategies for cross-page evidence. We further consolidate MP-VRDU datasets and outline open challenges in efficiency, faithfulness, evidence pipelines, supervision integrity, and reproducible evaluation that define the frontier.

Despite rapid progress in large language models (LLMs), current QA benchmarks still overlook the core challenge of real-world scientific information seeking: synthesizing multimodal evidence scattered across multiple documents and structural formats. Existing QAs remain narrow in scope, relying on unimodal text and short-span reasoning that fail to capture the complexity of real information-seeking. We introduce DocHop-QA, a benchmark of 11,379 instances for evaluating multimodal, multi-document, multi-hop scientific QA. Built from publicly available PubMed articles, DocHop-QA incorporates textual passages, tables, and layout cues, enabling cross-document inference without explicit hyperlinks. To scale realistic QA construction, we develop an LLM-driven generation pipeline grounded in 11 scientific reasoning concepts, producing diverse and coherent question–answer pairs. To highlight the utility and versatility of the dataset, we propose a task-driven evaluation framework spanning four settings, including generative answering, multimodal evidence integration and structured index prediction. Experiments show that current models struggle with DocHop-QA’s long-context, multi-evidence demands, establishing it as a rigorous testbed for advancing next-generation scientific QA systems.

Mineral exploration requires integrating heterogeneous geochemical, geophysical, and geological evidence, yet existing prospectivity systems often provide only opaque scores or heatmaps. We present MineTRACE, a web-based system for evidence-grounded exploration of eight commodities: Cu, Au, Ni, W, Sn, Co, Ta, and Mn. Users can explore prospectivity maps, query locations or regions, inspect supporting evidence, and interact through natural language. A transparent expert tree, informed by geological knowledge and known deposits, combines multi-source evidence into interpretable prospectivity scores. For a new location, the conversational assistant retrieves the score and supporting evidence from the analysis pipeline and presents them in natural language. The scorer achieves spatial AUC values of up to 0.917 across different test scenarios, while end-to-end evaluation assesses query accuracy and response grounding. MineTRACE makes public geoscience data easier to access, interpret, and verify, supporting more efficient and transparent mineral exploration. Our video is available via https://geo.nlp-tlp.org/video, live demo is available via https://geo.nlp-tlp.org.

Automated 3D radiology report generation often suffers from clinical hallucinations and a lack of the iterative verification found in human practice. While recent Vision-Language Models (VLMs) have advanced the field, they typically operate as monolithic “black-box” systems without the collaborative oversight characteristic of clinical workflows. To address these challenges, we propose MARCH (Multi-Agent Radiology Clinical Hierarchy), a multi-agent framework that emulates the professional hierarchy of radiology departments and assigns specialized roles to distinct agents. MARCH utilizes a Resident Agent for initial drafting with multi-scale CT feature extraction, multiple Fellow Agents for retrieval-augmented revision, and an Attending Agent that orchestrates an iterative, stance-based consensus discourse to resolve diagnostic discrepancies. On the RadGenome-ChestCT dataset, MARCH significantly outperforms state-of-the-art baselines in both clinical fidelity and linguistic accuracy. Our work demonstrates that modeling human-like organizational structures enhances the reliability of AI in high-stakes medical domains.

Current Multimodal Large Language Models (MLLMs) excel in general visual reasoning but remain underexplored in Abstract Visual Reasoning (AVR), which demands higher-order reasoning to identify abstract rules beyond simple perception. Existing AVR benchmarks focus on single-step reasoning, emphasizing the end result but neglecting the multi-stage nature of reasoning process. Past studies found MLLMs struggle with these benchmarks, but it doesn’t explain how they fail. To address this gap, we introduce MultiStAR, a Multi-Stage AVR benchmark, based on RAVEN, designed to assess reasoning across varying levels of complexity. Additionally, existing metrics like accuracy only focus on the final outcomes while do not account for the correctness of intermediate steps. Therefore, we propose a novel metric, MSEval, which considers the correctness of intermediate steps in addition to the final outcomes. We conduct comprehensive experiments on MultiStAR using 17 representative close-source and open-source MLLMs. The results reveal that while existing MLLMs perform adequately on basic perception tasks, they continue to face challenges in more complex rule detection stages. The dataset and code will be available after acceptance.

Evidence-based medicine (EBM) is at the forefront of modern healthcare, emphasizing the use of the best available scientific evidence to guide clinical decisions. Due to the sheer volume and rapid growth of medical literature and the high cost of curation, there is a critical need to investigate Natural Language Processing (NLP) methods to identify, appraise, synthesize, summarize, and disseminate evidence in EBM. This survey presents an in-depth review of 129 research studies on leveraging NLP for EBM, illustrating its pivotal role in enhancing clinical decision-making processes. The paper systematically explores how NLP supports the five fundamental steps of EBM—Ask, Acquire, Appraise, Apply, and Assess. The review not only identifies current limitations within the field but also proposes directions for future research, emphasizing the potential for NLP to revolutionize EBM by refining evidence extraction, evidence synthesis, appraisal, summarization, enhancing data comprehensibility, and facilitating a more efficient clinical workflow.

This paper presents a groundbreaking multimodal, multi-task, multi-teacher joint-grained knowledge distillation model for visually-rich form document understanding. The model is designed to leverage insights from both fine-grained and coarse-grained levels by facilitating a nuanced correlation between token and entity representations, addressing the complexities inherent in form documents. Additionally, we introduce new inter-grained and cross-grained loss functions to further refine diverse multi-teacher knowledge distillation transfer process, presenting distribution gaps and a harmonised understanding of form documents. Through a comprehensive evaluation across publicly available form document understanding datasets, our proposed model consistently outperforms existing baselines, showcasing its efficacy in handling the intricate structures and content of visually complex form documents.

Drug-drug interaction (DDI) may leads to adverse reactions in patients, thus it is important to extract such knowledge from biomedical texts. However, previously proposed approaches typically focus on capturing sentence-aspect information while ignoring valuable knowledge concerning the whole corpus. In this paper, we propose a Multi-aspect Graph-based DDI extraction model, named DDI-MuG. We first employ a bio-specific pre-trained language model to obtain the token contextualized representations. Then we use two graphs to get syntactic information from input instance and word co-occurrence information within the entire corpus, respectively. Finally, we combine the representations of drug entities and verb tokens for the final classification. It is encouraging to see that the proposed model outperforms all baseline models on two benchmark datasets. To the best of our knowledge, this is the first model that explores multi-aspect graphs to the DDI extraction task, and we hope it can establish a foundation for more robust multi-aspect works in the future.

Recognizing the layout of unstructured digital documents is crucial when parsing the documents into the structured, machine-readable format for downstream applications. Recent studies in Document Layout Analysis usually rely on visual cues to understand documents while ignoring other information, such as contextual information or the relationships between document layout components, which are vital to boost better layout analysis performance. Our Doc-GCN presents an effective way to harmonize and integrate heterogeneous aspects for Document Layout Analysis. We construct different graphs to capture the four main features aspects of document layout components, including syntactic, semantic, density, and appearance features. Then, we apply graph convolutional networks to enhance each aspect of features and apply the node-level pooling for integration. Finally, we concatenate features of all aspects and feed them into the 2-layer MLPs for document layout component classification. Our Doc-GCN achieves state-of-the-art results on three widely used DLA datasets: PubLayNet, FUNSD, and DocBank. The code will be released at https://github.com/adlnlp/doc_gcn