The deployment of Large Language Models (LLMs) in interactive systems necessitates a deep alignment with the nuanced and dynamic preferences of individual users. Current alignment techniques predominantly address universal human values or static, single-turn preferences, thereby failing to address the critical needs of long-term personalization and the initial user cold-start problem. To bridge this gap, we propose PersonalAgent, a novel user-centric lifelong agent designed to continuously infer and adapt to user preferences. PersonalAgent constructs and dynamically refines a unified user profile by decomposing dialogues into single-turn interactions, framing preference inference as a sequential decision-making task. Experiments show that PersonalAgent achieves superior performance over strong prompt-based and policy optimization baselines, not only in idealized but also in noisy conversational contexts, while preserving cross-session preference consistency. Furthermore, human evaluation confirms that PersonalAgent excels at capturing user preferences naturally and coherently. Our findings underscore the importance of lifelong personalization for developing more inclusive and adaptive conversational agents. Our code and ALOE-Unseen dataset are released here.

While reinforcement learning from verifiable rewards (RLVR) has been proven highly effective for enhancing reasoning, its application to medical visual question answering (Med-VQA) is hampered by models producing reasoning inconsistent with either the visual evidence or the final answer. Our analysis reveals a critical flaw in RLVR training: it paradoxically encourages models to disregard visual evidence and generate answers that contradict their own reasoning. This degradation is most pronounced in specialized medical modalities (e.g., Fundus, Ultrasound) where base VLMs lack robust understanding, a failure we attribute to a flawed reward mechanism exacerbated by the scarcity of diverse training data. To tackle this, we introduce Med-Zero-17K, a large-scale dataset spanning over 30 modalities and 24 clinically relevant tasks, and the Multi-Consistency Reward (MCR) framework, which explicitly rewards both perceptual grounding and logical coherence. Extensive experiments validate our approach: integrating MCR into the RLVR framework delivers robust performance gains. This success stems from our crucial finding that rewarding internal consistency is significantly more effective than attempting to judge reasoning correctness. Furthermore, MCR proves highly versatile, exhibiting strong generalization across diverse VLM backbones, compatibility with RL algorithms like GRPO and DPO, and extending its effectiveness to 3D VQA tasks and R1-style training paradigms. Code and dataset will be released.

Artificial intelligence has advanced in Medical Visual Question Answering (Med-VQA), but prevalent research tends to focus on the accuracy of the answers, often overlooking the reasoning paths and interpretability, which are crucial in clinical settings. Besides, current Med-VQA algorithms, typically reliant on singular models, lack the robustness needed for real-world medical diagnostics which usually require collaborative expert evaluation. To address these shortcomings, this paper presents MedCoT, a novel hierarchical expert verification reasoning chain method designed to enhance interpretability and accuracy in biomedical imaging inquiries. MedCoT is predicated on two principles: The necessity for explicit reasoning paths in Med-VQA and the requirement for multi-expert review to formulate accurate conclusions. The methodology involves an Initial Specialist proposing diagnostic rationales, followed by a Follow-up Specialist who validates these rationales, and finally, a consensus is reached through a vote among a sparse Mixture of Experts within the locally deployed Diagnostic Specialist, which then provides the definitive diagnosis. Experimental evaluations on four standard Med-VQA datasets demonstrate that MedCoT surpasses existing state-of-the-art approaches, providing significant improvements in performance and interpretability.