Large language models with billions of parameters are often over-provisioned: many layers contribute little unique information yet dominate the memory and energy footprint during inference. We present LieQ (Layer-wise information effectiveness Quantization), a hardware-native, metric-driven post-training quantization framework that addresses the critical challenge of maintaining accuracy in sub-8B models, model parameters less than 8B, under extreme low-bit compression. LieQ keeps uniform bit-width within each layer while mixing precision across layers, preserving standard multiplication kernels and avoiding irregular memory access, codebooks, or irregular formats at inference time. Our method uncovers a strong correlation between layer-wise functional saliency and representational compactness, revealing that layers with higher training-induced energy concentration are functionally irreplaceable. Leveraging this insight, we propose a purely geometry-driven sensitivity proxy that enables automatic bit-width allocation under a target average-bit budget without expensive gradient updates or inference-based perplexity probing. Under an average weight bit-width approaching two bits per parameter, LieQ consistently reduces the large accuracy gap typically observed for naive uniform 2-bit baselines on Qwen3 and LLaMA3.x families, while retaining standard-kernel efficiency. These properties make LieQ a practical path toward deploying small language models on resource-constrained edge devices. Code will be available at: https://github.com/HeXiao-55/LieQ-official.git.

Mechanistic Interpretability (MI) has emerged as a vital approach to demystify the opaque decision-making of Large Language Models (LLMs). However, existing reviews primarily treat MI as an observational science, summarizing analytical insights while lacking a systematic framework for actionable intervention. To bridge this gap, we present a practical survey structured around the pipeline: “Locate, Steer, and Improve.” We formally categorize Localizing (diagnosis) and Steering (intervention) methods based on specific Interpretable Objects to establish a rigorous intervention protocol. Furthermore, we demonstrate how this framework enables tangible improvements in Alignment, Capability, and Efficiency, effectively operationalizing MI as a practical engineering toolkit for model optimization. The curated paper list of this work is available at https://anonymous.4open.science/r/Act-MI-F068.

Layer-wise mixed-precision quantization (LMPQ) enables effective compression under extreme low-bit settings by allocating higher precision to sensitive layers. However, existing methods typically treat all intra-layer weight modules uniformly and rely on a single numerical property when estimating sensitivity, overlooking their distinct operational roles and structural characteristics. To address this, we propose NSDS, a novel calibration-free LMPQ framework driven by Numerical and Structural Dual-Sensitivity. Specifically, it first mechanistically decomposes each layer into distinct operational roles and quantifies their sensitivity from both numerical and structural perspectives. These dual-aspect scores are then aggregated into a unified layer-wise metric through a robust aggregation scheme based on MAD-Sigmoid and Soft-OR to guide bit allocation. Extensive experiments demonstrate that NSDS consistently achieves superior performance compared to various baselines across diverse models and downstream tasks, without relying on any calibration data. The code is available at https://anonymous.4open.science/r/NSDS-DC56.