Current video-guided machine translation (VMT) approaches primarily use coarse-grained visual information, resulting in information redundancy, high computational overhead, and neglect of audio content. Our research demonstrates the significance of fine-grained visual and audio information in VMT from both data and methodological perspectives. From the data perspective, we have developed a large-scale dataset TriFine, the first vision-audio-subtitle tri-modal VMT dataset with annotated multimodal fine-grained tags. Each entry in this dataset not only includes the triples found in traditional VMT datasets but also encompasses seven fine-grained annotation tags derived from visual and audio modalities. From the methodological perspective, we propose a Fine-grained Information-enhanced Approach for Translation (FIAT). Experimental results have shown that, in comparison to traditional coarse-grained methods and text-only models, our fine-grained approach achieves superior performance with lower computational overhead. These findings underscore the pivotal role of fine-grained annotated information in advancing the field of VMT.