The capacity of Large Language Models (LLMs) to comprehend and reason over long contexts is pivotal for advancements in diverse fields. Yet, they still stuggle with capturing long-distance dependencies within sequences to deeply understand semantics. To address this issue, we introduce Query-aware Inference for LLMs (Q-LLM), a system designed to process extensive sequences akin to human cognition. By focusing on memory data relevant to a given query, Q-LLM can accurately capture pertinent information within a fixed window size and provide precise answers to queries. It doesn’t require extra training and can be seamlessly integrated with any LLMs. Q-LLM using LLaMA3 (QuickLLaMA) can read Harry Potter within 30s and accurately answer the questions. On widely recognized benchmarks, Q-LLM improved by 7.17% compared to the current state-of-the-art on LLaMA3, and by 3.26% on Mistral on the ∞-bench. In the Needle-in-a-Haystack and BABILong task, Q-LLM improved upon the current SOTA by 7.0% and 6.1%. Our code is in https://github.com/dvlab-research/Q-LLM.