Ojas Gramopadhye
2024
Few shot chain-of-thought driven reasoning to prompt LLMs for open-ended medical question answering
Saeel Sandeep Nachane
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Ojas Gramopadhye
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Prateek Chanda
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Ganesh Ramakrishnan
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Kshitij Sharad Jadhav
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Yatin Nandwani
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Dinesh Raghu
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Sachindra Joshi
Findings of the Association for Computational Linguistics: EMNLP 2024
In this paper, we propose a modified version of the MedQA-USMLE dataset, named MEDQA-OPEN, which contains open-ended medical questions without options to mimic clinical scenarios, along with clinician-approved reasoned answers. Additionally, we implement a prompt driven by Chain of Thought (CoT) reasoning, CLINICR, to mirror the prospective process of incremental reasoning, reaching a correct response to medical questions. We empirically demonstrate how CLINICR outperforms the state-of-the-art 5-shot CoT-based prompt (Liévin et al., 2022). We also present an approach that mirrors real-life clinical practice by first exploring multiple differential diagnoses through MCQ-CLINICR and subsequently narrowing down to a final diagnosis using MCQ-ELIMINATIVE. Finally, emphasizing the importance of response verification in medical settings, we utilize a reward model mechanism, replacing the elimination process performed by MCQ-ELIMINATIVE.
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