The spread of misinformation on social media platforms threatens democratic processes, contributes to massive economic losses, and endangers public health. Many efforts to address misinformation focus on a knowledge deficit model and propose interventions for improving users’ critical thinking through access to facts. Such efforts are often hampered by challenges with scalability, and by platform users’ personal biases. The emergence of generative AI presents promising opportunities for countering misinformation at scale across ideological barriers. In this paper, we introduce a framework (MisinfoEval) for generating and comprehensively evaluating large language model (LLM) based misinformation interventions. We present (1) an experiment with a simulated social media environment to measure effectiveness of misinformation interventions, and (2) a second experiment with personalized explanations tailored to the demographics and beliefs of users with the goal of countering misinformation by appealing to their pre-existing values. Our findings confirm that LLM-based interventions are highly effective at correcting user behavior (improving overall user accuracy at reliability labeling by up to 41.72%). Furthermore, we find that users favor more personalized interventions when making decisions about news reliability and users shown personalized interventions have significantly higher accuracy at identifying misinformation.

Large language models (LLMs) are already being piloted for clinical use in hospital systems like NYU Langone, Dana-Farber and the NHS. A proposed deployment use case is psychotherapy, where a LLM-powered chatbot can treat a patient undergoing a mental health crisis. Deployment of LLMs for mental health response could hypothetically broaden access to psychotherapy and provide new possibilities for personalizing care. However, recent high-profile failures, like damaging dieting advice offered by the Tessa chatbot to patients with eating disorders, have led to doubt about their reliability in high-stakes and safety-critical settings.In this work, we develop an evaluation framework for determining whether LLM response is a viable and ethical path forward for the automation of mental health treatment. Our framework measures equity in empathy and adherence of LLM responses to motivational interviewing theory. Using human evaluation with trained clinicians and automatic quality-of-care metrics grounded in psychology research, we compare the responses provided by peer-to-peer responders to those provided by a state-of-the-art LLM.We show that LLMs like GPT-4 use implicit and explicit cues to infer patient demographics like race. We then show that there are statistically significant discrepancies between patient subgroups: Responses to Black posters consistently have lower empathy than for any other demographic group (2%-13% lower than the control group). Promisingly, we do find that the manner in which responses are generated significantly impacts the quality of the response. We conclude by proposing safety guidelines for the potential deployment of LLMs for mental health response.

Multiple Sclerosis (MS) is a chronic, inflammatory and degenerative neurological disease, which is monitored by a specialist using the Expanded Disability Status Scale (EDSS) and recorded in unstructured text in the form of a neurology consult note. An EDSS measurement contains an overall ‘EDSS’ score and several functional subscores. Typically, expert knowledge is required to interpret consult notes and generate these scores. Previous approaches used limited context length Word2Vec embeddings and keyword searches to predict scores given a consult note, but often failed when scores were not explicitly stated. In this work, we present MS-BERT, the first publicly available transformer model trained on real clinical data other than MIMIC. Next, we present MSBC, a classifier that applies MS-BERT to generate embeddings and predict EDSS and functional subscores. Lastly, we explore combining MSBC with other models through the use of Snorkel to generate scores for unlabelled consult notes. MSBC achieves state-of-the-art performance on all metrics and prediction tasks and outperforms the models generated from the Snorkel ensemble. We improve Macro-F1 by 0.12 (to 0.88) for predicting EDSS and on average by 0.29 (to 0.63) for predicting functional subscores over previous Word2Vec CNN and rule-based approaches.

Models that perform well on a training domain often fail to generalize to out-of-domain (OOD) examples. Data augmentation is a common method used to prevent overfitting and improve OOD generalization. However, in natural language, it is difficult to generate new examples that stay on the underlying data manifold. We introduce SSMBA, a data augmentation method for generating synthetic training examples by using a pair of corruption and reconstruction functions to move randomly on a data manifold. We investigate the use of SSMBA in the natural language domain, leveraging the manifold assumption to reconstruct corrupted text with masked language models. In experiments on robustness benchmarks across 3 tasks and 9 datasets, SSMBA consistently outperforms existing data augmentation methods and baseline models on both in-domain and OOD data, achieving gains of 0.8% on OOD Amazon reviews, 1.8% accuracy on OOD MNLI, and 1.4 BLEU on in-domain IWSLT14 German-English.