We propose ELAINE (EngLish-jApanese-chINesE)-medLLM, a trilingual (English, Japanese, Chinese) large language model adapted for the bio-medical domain based on Llama-3-8B. The training dataset was carefully curated in terms of volume and diversity to adapt to the biomedical domain and endow trilingual capability while preserving the knowledge and abilities of the base model. The training follows 2-stage paths: continued pre-training and supervised fine-tuning (SFT). Our results demonstrate that ELAINE-medLLM exhibits superior trilingual capabilities compared to existing bilingual or multilingual medical LLMs without severely sacrificing the base model’s capability.

We propose a distantly supervised pipeline NER which executes entity span detection and entity classification in sequence named DISTANT (DIstantly Supervised enTity spAN deTection and classification).The former entity span detector extracts possible entity mention spans by the distant supervision. Then the later entity classifier assigns each entity span to one of the positive entity types or none by employing a positive and unlabeled (PU) learning framework. Two models were built based on the pre-trained SciBERT model and fine-tuned with the silver corpus generated by the distant supervision. Experimental results on BC5CDR and NCBI-Disease datasets show that our method outperforms the end-to-end NER baselines without PU learning by a large margin. In particular, it increases the recall score effectively.